Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Perrache | Terminal Bus Palermo | No tags | ||||
| Bus | Perrache | Terminal Bus Palermo | No tags | ||||
| Bus | Perrache | Terminal Bus Palermo | No tags | ||||
| Bus | Aéroport LYS | Terminal Bus Palermo | No tags | ||||
| Bus | Perrache | Terminal Bus Palermo | No tags |
Get from Lyon to Palermo
The journey takes about 1 day, 11 hours 30 minutes, and with fares starting at just £129, it presents an excellent value for a comfortable ride.
Where are the popular stops in Lyon and Palermo?
Stops in Lyon
- ARue de Esplanade, 69002 Lyon, France
- C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - FLes Charrières, 69570 Dardilly, France
Stops in Palermo
- AVia Tommaso Fazello, 16, 90123 Palermo PA, Italy
- BPunta Raisi, 90145, Palermo
- CPiazza Cairoli, 8-14, 90123 Palermo, Italy
- D90143 Palermo PA, Italy
- EVia Paolo Balsamo, 21, 90123 Palermo, Italy
- F
Via Paolo Balsamo, 31
Via Paolo Balsamo, 23-31, 90123 Palermo, Italy
Compare bus companies
Based on 11693 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at £129
Frequently asked questions about travelling by bus from Lyon to Palermo
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Lyon to Palermo?
The cheapest coach tickets from Lyon to Palermo start from £129. The average price for this route is around £145. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Lyon to Palermo?
The average bus journey time from Lyon to Palermo is 1d 11h, covering a distance of 685 miles. The fastest bus can take you there in 1d 7h and is operated by FlixBus.
Which bus companies service the Lyon to Palermo route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Lyon to Palermo?
The earliest bus departs from Lyon to Palermo at 03:25. And the latest bus departs at 23:30.
What are the CO₂ emissions for the bus trip from Lyon to Palermo?
A bus journey from Lyon to Palermo produces an estimated 28 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Lyon to Palermo was searched and found on 25 Dec 2025 with a price of £126To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Palermo as early as possible.
You can expect to pay from £126 to £158 for a bus ticket from Lyon to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at £126, which is on 2025-12-25.
