Next departures for Los Mochis to Guadalajara on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Los Mochis Bus Station
Nueva Central
Cheapest
Bus
Los Mochis Bus Station
Zapopan Central de Autobuses (Guadalajara)
Fastest
Bus
Los Mochis Bus Station
Nueva Central
No tags
Bus
Los Mochis Bus Station
Nueva Central
No tags
Bus
Los Mochis Bus Station
Nueva Central
No tags
Next departures for Los Mochis to Guadalajara on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Los Mochis - Stop
Guadalajara Zapopan - Stop
Cheapest
Bus
Los Mochis Bus Station
Zapopan Central de Autobuses (Guadalajara)
Fastest
Bus
Los Mochis Bus Station, Blvd Rosendo G Castro y Av. Constitución 302, Los Mochis
Zapopan Central de Autobuses (Guadalajara)
No tags
Bus
Los Mochis - Stop
Nueva Central
No tags
Bus
Los Mochis Bus Station
Nueva Central
No tags
Next departures for Los Mochis to Guadalajara on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Los Mochis - Stop
Guadalajara Zapopan - Stop
Cheapest
Bus
Los Mochis Bus Station
Zapopan Central de Autobuses (Guadalajara)
Fastest
Bus
Los Mochis Bus Station, Blvd Rosendo G Castro y Av. Constitución 302, Los Mochis
Zapopan Central de Autobuses (Guadalajara)
No tags
Bus
Los Mochis - Stop
Nueva Central
No tags
Bus
Los Mochis Bus Station
Nueva Central
No tags
Next departures for Los Mochis to Guadalajara on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Los Mochis - Stop
Guadalajara Zapopan - Stop
Cheapest
Bus
Los Mochis Bus Station
Zapopan Central de Autobuses (Guadalajara)
Fastest
Bus
Los Mochis Bus Station, Blvd Rosendo G Castro y Av. Constitución 302, Los Mochis
Zapopan Central de Autobuses (Guadalajara)
No tags
Bus
Los Mochis - Stop
Nueva Central
No tags
Bus
Los Mochis Bus Station
Nueva Central
No tags
Next departures for Los Mochis to Guadalajara on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Los Mochis - Stop
Guadalajara Zapopan - Stop
Cheapest
Bus
Los Mochis Bus Station
Zapopan Central de Autobuses (Guadalajara)
Fastest
Bus
Los Mochis Bus Station, Blvd Rosendo G Castro y Av. Constitución 302, Los Mochis
Zapopan Central de Autobuses (Guadalajara)
No tags
Bus
Los Mochis - Stop
Nueva Central
No tags
Bus
Los Mochis Bus Station
Nueva Central
No tags
Next departures for Los Mochis to Guadalajara on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Los Mochis - Stop
Guadalajara Zapopan - Stop
CheapestFastest
Bus
Los Mochis Bus Station, Blvd Rosendo G Castro y Av. Constitución 302, Los Mochis
Zapopan Central de Autobuses (Guadalajara)
No tags
Bus
Los Mochis - Stop
Nueva Central
No tags
Bus
Los Mochis Bus Station
Nueva Central
No tags
Bus
LOS MOCHIS - Stop
Av de las Torres
No tags
Last refresh of the prices: Yesterday at 10:52 PM MST.
Compare 2 ways to go from Los Mochis to Guadalajara
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as the good way to reach Guadalajara. The journey takes about 10 hours 50 minutes and with fares starting at just $44, it presents an excellent value for a comfortable ride.
Based on 167 reviews, the company was rated 2.5 stars on Busbud. Travelers were especially satisfied with the seats and the temperature but often complained with the wifi. Elite ticket prices on this trip start at $104
Since 1994, Tufesa has been offering comfortable, safe, and affordable bus travel in the United States (California, Nevada, Utah, Arizona and Texas) and Mexico (Baja California Sur, Sonora, Sinaloa and Guadalajara). Tufesa buses are equipped with comfortable reclining seats, power outlets, bathrooms, and WiFi (only in Mexico). Tickets are non-refundable, but you can exchange them up to 1 hour before travel time for a small fee. The company accepts e-tickets, so you don't have to worry about printing your boarding pass. With over 9 daily trips, you'll surely find a convenient trip that fits your needs and your schedule.
Based on 20 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the departure location but often complained with the wifi. Turistar ticket prices on this trip start at $135
If you're looking for an affordable, comfortable way to travel through the pacific region of Mexico and the United States, then ACN is a good option. With more than 300 buses, the company travels through over 700 routes in the two countries, connecting over 50 cities with an average of 600 daily buses. With a modern fleet, ACN buses have WiFi, reclining comfy seats, power outlets, onboard entertainment, and bathrooms.
Based on 15 reviews, the company was rated 3 stars on Busbud. Travelers were especially satisfied with the seats and the cleanliness but often complained with the timeliness. ELITE SELECT ticket prices on this trip start at $107
Based on 23 reviews, the company was rated 1.5 stars on Busbud. Travelers were especially satisfied with the ticket access and the seats but often complained with the power outlets. Autotravel ticket prices on this trip start at $70
Based on 736 reviews, the company was rated 3.4 stars on Busbud. Travelers were especially satisfied with the seats and the departure location but often complained with the wifi. Futura ticket prices on this trip start at $94
Based on 167 reviews, the company was rated 2.5 stars on Busbud. Travelers were especially satisfied with the seats and the temperature but often complained with the wifi. Elite ticket prices on this trip start at $104
If you're looking for an affordable, comfortable way to travel through the pacific region of Mexico and the United States, then ACN is a good option. With more than 300 buses, the company travels through over 700 routes in the two countries, connecting over 50 cities with an average of 600 daily buses. With a modern fleet, ACN buses have WiFi, reclining comfy seats, power outlets, onboard entertainment, and bathrooms.
Based on 160 reviews, the company was rated 3.1 stars on Busbud. Travelers were especially satisfied with the ticket access and the seats but often complained with the wifi. Chihuahuenses ticket prices on this trip start at $219
Since 1994, Tufesa has been offering comfortable, safe, and affordable bus travel in the United States (California, Nevada, Utah, Arizona and Texas) and Mexico (Baja California Sur, Sonora, Sinaloa and Guadalajara). Tufesa buses are equipped with comfortable reclining seats, power outlets, bathrooms, and WiFi (only in Mexico). Tickets are non-refundable, but you can exchange them up to 1 hour before travel time for a small fee. The company accepts e-tickets, so you don't have to worry about printing your boarding pass. With over 9 daily trips, you'll surely find a convenient trip that fits your needs and your schedule.
Based on 32 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the departure location and the cleanliness but often complained with the wifi. Aguacaliente ticket prices on this trip start at $93
TIM Express offers 1 daily buses from Los Mochis to Guadalajara. Though the average price for this trip is $50, you can find tickets starting at $49. The trip between the two cities usually takes about 900.
Based on 3 reviews, the company was rated 3.6 stars on Busbud. Travelers were especially satisfied with the departure location and the timeliness but often complained with the wifi. Interbus de Sinaloa ticket prices on this trip start at $59
Based on 32 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the departure location and the cleanliness but often complained with the wifi. Aguacaliente ticket prices on this trip start at $93
Based on 22 reviews, the company was rated 2 stars on Busbud. Travelers were especially satisfied with the seats and the departure location but often complained with the wifi. Nayar ticket prices on this trip start at $78
Norte de Sonora offers 2 daily departures, and you can find tickets starting at $78. The quickest ride takes around 790. Norte de Sonora offers a cost-effective solution to get you where you need to be.
Frequently asked questions about traveling from Los Mochis to Guadalajara, MX by bus
What is the distance between Los Mochis and Guadalajara?
The distance separating Los Mochis and Guadalajara is 502 miles (809 km).
What are the departure and arrival stations when taking the bus from Los Mochis to Guadalajara?
If you're headed to Guadalajara from Los Mochis, chances are that your bus will leave from José María Morelos y Pavón 356 and arrive at Nueva Central. These are the main pick-up and drop-off locations on this route, but you could find others that could be a better fit for your travel plans.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/20
$55
11/21
$55
Today
$55
11/23
$55
11/24
$55
11/25
$55
11/26
$55
11/27
$55
The cheapest trip from Los Mochis to Guadalajara, MX was searched and found on Nov 24, 2025 with a price of $55
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Los Mochis to Guadalajara, MX, as early as possible.
You can expect to pay from $55 to $127 for a bus ticket from Los Mochis to Guadalajara, MX based on the last 2 days. You can expect to find the cheapest price for the trip at $55 which is on 2025-11-24.
Usually Turistar will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from Los Mochis to Guadalajara, MX was searched and found on Nov 24, 2025 with a price of $55
