Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Las Cruces (Mesilla Valley Intermodal Transit Terminal) | San Antonio Bus Station | CheapestFastest | ||||
Greyhound Lines, Inc. + Valley Transit | Bus | Las Cruces (Mesilla Valley Intermodal Transit Terminal) | San Antonio Bus Station | No tags |
Last refresh of the prices: Yesterday at 3:59 PM MST.
Get from Las Cruces to San Antonio
The journey takes about 20 hours 5 minutes and with fares starting at just $121, it presents an excellent value for a comfortable ride.
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Las Cruces, US to San Antonio, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Las Cruces to San Antonio?
The cheapest bus tickets from Las Cruces to San Antonio start from $121. The average price for this route is around $148. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Las Cruces to San Antonio?
The average bus trip duration from Las Cruces to San Antonio is 20h 5m, covering a distance of 529 miles (854 km). The quickest bus can get you there in 12h 35m and is operated by Greyhound.
Which bus companies service the Las Cruces to San Antonio route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Las Cruces to San Antonio?
The earliest bus departs from Las Cruces to San Antonio at 10:50am. And the latest bus departs at 3:50pm.
What are the CO₂ emissions for the bus trip from Las Cruces to San Antonio?
A bus trip from Las Cruces to San Antonio generates an estimated 21 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Las Cruces, US to San Antonio, US was searched and found on Jan 6, 2026 with a price of $124To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Las Cruces, US to San Antonio, US, as early as possible.
You can expect to pay from $124 to $179 for a bus ticket from Las Cruces, US to San Antonio, US based on the last 0 days. You can expect to find the cheapest price for the trip at $124 which is on 2026-01-06.
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