How far is Knoxville from Cincinnati?

The distance separating Knoxville and Cincinnati is 223 miles (360 km).

What are the departure and arrival stations when taking the bus from Knoxville to Cincinnati?

Most of the buses traveling from Knoxville to Cincinnati leave from 100 Kirkwood St and arrive at Greyhound Station. These are the most popular pick-up and drop-off locations on this route, but you can find others that could fit better into your travel plans.

Bus Knoxville to Cincinnati from $35 | Refundable Tickets

Previously seen trips

Next departures for Knoxville to Cincinnati on November 23
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	10:30pm	Knoxville Bus Station	5h 15m	3:45am	Cincinnati Bus Station	No tags
Bus	10:30pm	Knoxville Bus Station	5h 15m	3:45am	Cincinnati Bus Station	No tags
Bus	10:30pm	Knoxville Bus Station	5h 15m	3:45am	Cincinnati Bus Station	No tags
Bus	10:30pm	Knoxville Bus Station	5h 15m	3:45am	Cincinnati Bus Station	No tags
Bus	10:15pm	Knoxville Bus Station	5h 30m	3:45am	Cincinnati Bus Station	No tags

Get from Knoxville to Cincinnati

This route is served by bus only

The journey takes about 5 hours 25 minutes and with fares starting at just $43, it presents an excellent value for a comfortable ride.

1bus per day

5h 25mAverage Duration

224 milesDistance

9kgCO₂ emissions

Where are the popular stops in Knoxville and Cincinnati?

Stops in Knoxville

A
100 Kirkwood St
Knoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Visit page

Stops in Cincinnati

A
Greyhound Station
1005 Gilbert Ave, Cincinnati, OH 45202
Visit page
B
Northland Blvd
290-322 Northland Blvd, Springdale, OH 45246, USA

Compare bus companies

Greyhound

3.5/587,391 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

Greyhound Knoxville Cincinnati recent customer reviews

Very nice trip

Paula L.

May 21, 2017

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Knoxville, TN to Cincinnati by bus

How far is Knoxville from Cincinnati?
What are the departure and arrival stations when taking the bus from Knoxville to Cincinnati?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/21

$43

11/22

$46

Today

$53

11/24

$49

11/25

$52

11/26

$58

11/27

$53

11/28

$53

The cheapest trip from Knoxville, TN to Cincinnati was searched and found on Nov 21, 2025 with a price of $43

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Cincinnati, as early as possible.

You can expect to pay from $43 to $58 for a bus ticket from Knoxville, TN to Cincinnati based on the last 2 days. You can expect to find the cheapest price for the trip at $49 which is on 2025-11-24.