Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Arturo Prat Chacón / Terminal Rodiviario | Santa Cruz de la Sierra | CheapestFastest |
Last refresh of the prices: Yesterday at 12:32 PM -03.
Get from Iquique to Santa Cruz de la Sierra
The journey takes about 1 day, 3 hours 30 minutes and with fares starting at just $77, it presents an excellent value for a comfortable ride.
Where are the popular stops in Iquique and Santa Cruz de la Sierra?
Stops in Iquique
- APatricio Lynch 60, Iquique, Región de Tarapacá, Chile
- B
Guatacondo 3430
Guatacondo 3430, Iquique, Región de Tarapacá, Chile - C
Eleuterio Ramirez 594
Eleuterio Ramirez 594, Iquique, Región de Tarapacá, Chile - D
Av. Salvador Allende Gossens 2360
Av. Salvador Allende Gossens 2360, Iquique, Región de Tarapacá, Chile - E
Camarones
Arturo Pérez Canto 2227-2299, Iquique, Región de Tarapacá, Chile - F
Huara
Huara 2963, Iquique, Región de Tarapacá, Chile
Stops in Santa Cruz de la Sierra
- AAv Intermodal, Santa Cruz de la Sierra, Bolivia
Compare bus companies
A good way to travel this route is with Bus Fer buses. The company offers 1 daily departures, with ticket prices starting at $77 and the shortest trip taking about 1650. Bus Fer gets you where you want to go for a fair price.
Frequently asked questions about traveling from Iquique to Santa Cruz de la Sierra, BO by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Iquique to Santa Cruz de la Sierra?
The cheapest bus tickets from Iquique to Santa Cruz de la Sierra start from $77. The average price for this route is around $93. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Iquique to Santa Cruz de la Sierra?
The average bus trip duration from Iquique to Santa Cruz de la Sierra is 1d 3h, covering a distance of 486 miles (783 km). The quickest bus can get you there in 1d 3h and is operated by Bus Fer.
Which bus companies service the Iquique to Santa Cruz de la Sierra route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Iquique to Santa Cruz de la Sierra?
The earliest bus departs from Iquique to Santa Cruz de la Sierra at 10:30am. And the latest bus departs at 7:00pm.
What are the CO₂ emissions for the bus trip from Iquique to Santa Cruz de la Sierra?
A bus trip from Iquique to Santa Cruz de la Sierra generates an estimated 20 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Iquique to Santa Cruz de la Sierra, BO was searched and found on Nov 30, 2025 with a price of $73To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Iquique to Santa Cruz de la Sierra, BO, as early as possible.
You can expect to pay from $73 to $88 for a bus ticket from Iquique to Santa Cruz de la Sierra, BO based on the last 2 days. You can expect to find the cheapest price for the trip at $88 which is on 2025-12-02.
