How much is the bus ticket from Harrisburg to Indianapolis?

The cheapest bus tickets from Harrisburg to Indianapolis start from $71. The average price for this route is around $119. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Harrisburg to Indianapolis?

The average bus trip duration from Harrisburg to Indianapolis is 14h, covering a distance of 492 miles (793 km). The quickest bus can get you there in 11h 10m and is operated by Greyhound .

Which bus companies service the Harrisburg to Indianapolis route?

Several major bus companies operate on this route with 8 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from Harrisburg to Indianapolis?

The earliest bus departs from Harrisburg to Indianapolis at 1:30am. And the latest bus departs at 9:10pm.

What are the CO₂ emissions for the bus trip from Harrisburg to Indianapolis?

A bus trip from Harrisburg to Indianapolis generates an estimated 20 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Harrisburg to Indianapolis?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87387 reviews.

Which bus company has the best Wi-Fi from Harrisburg to Indianapolis?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Harrisburg to Indianapolis?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Harrisburg to Indianapolis?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Harrisburg to Indianapolis from $63 | Refundable Tickets

Next bus departures

Next departures for Harrisburg to Indianapolis on December 1
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	7:45pm	Harrisburg Bus Station	14h	9:45am	Indianapolis Bus Station	Cheapest
Bus	2:05pm	Harrisburg Bus Station	12h 10m	2:15am	Indianapolis Bus Station	Fastest
Bus	2:30am	Harrisburg Bus Station	16h 10m	6:40pm	Indianapolis Bus Station	No tags
Bus	1:20pm	Harrisburg Bus Station	12h 55m	2:15am	Indianapolis Bus Station	No tags
Bus	8:15pm	Harrisburg Bus Station	13h 30m	9:45am	Indianapolis Bus Station	No tags

Last refresh of the prices: Yesterday at 4:34 AM EST.

Compare 2 ways to go from Harrisburg to Indianapolis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Indianapolis. The journey takes about 14 hours and with fares starting at just $71, it presents an excellent value for a comfortable ride.

8bus per day

14hAverage Duration

492 milesDistance

20kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$71 - $377	Average Duration14h	CO₂ emissions 20kg CO₂e
Train	Average Price$160 - $675	Average Duration1d 9h	CO₂ emissions 72kg CO₂e

Where are the popular stops in Harrisburg and Indianapolis?

Stops in Harrisburg

A
Harrisburg Bieber Greyhound Station
411 Market St, Harrisburg, PA 17101

Stops in Indianapolis

A
Greyhound Amtrak Station
350 S Illinois St, Indianapolis, IN 46225
Visit page

Compare bus companies

Greyhound

3.5/587,408 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,476 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Harrisburg to Indianapolis by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Harrisburg to Indianapolis?
The cheapest bus tickets from Harrisburg to Indianapolis start from $71. The average price for this route is around $119. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Harrisburg to Indianapolis?
The average bus trip duration from Harrisburg to Indianapolis is 14h, covering a distance of 492 miles (793 km). The quickest bus can get you there in 11h 10m and is operated by Greyhound.
Which bus companies service the Harrisburg to Indianapolis route?
Several major bus companies operate on this route with 8 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Harrisburg to Indianapolis?
The earliest bus departs from Harrisburg to Indianapolis at 1:30am. And the latest bus departs at 9:10pm.
What are the CO₂ emissions for the bus trip from Harrisburg to Indianapolis?
A bus trip from Harrisburg to Indianapolis generates an estimated 20 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Harrisburg to Indianapolis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from Harrisburg to Indianapolis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Harrisburg to Indianapolis?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Harrisburg to Indianapolis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/28

$108

11/29

$152

Today

$182

12/01

$143

12/02

$78

12/03

$71

12/04

$63

12/05

No data

The cheapest trip from Harrisburg to Indianapolis was searched and found on Dec 4, 2025 with a price of $63

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to Indianapolis, as early as possible.

You can expect to pay from $63 to $369 for a bus ticket from Harrisburg to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $63 which is on 2025-12-04.