What is the travel distance from Harrisburg to Indianapolis?

The distance between Harrisburg and Indianapolis is around 793 km (492 miles).

What are the departure and arrival locations for buses traveling from Harrisburg to Indianapolis?

Buses traveling this route start their trip at Harrisburg Bieber Greyhound Station, in Harrisburg, and end it at Greyhound Amtrak Station, in Indianapolis.

Bus Harrisburg to Indianapolis from $91 | Refundable Tickets

Next bus departures

Next departures for Harrisburg to Indianapolis on November 26
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	1:20pm	Harrisburg Bus Station	12h 55m	2:15am	Indianapolis Bus Station	Cheapest
	Bus	2:05pm	Harrisburg Bus Station	12h 10m	2:15am	Indianapolis Bus Station	Fastest
	Bus	7:45pm	Harrisburg Bus Station	14h	9:45am	Indianapolis Bus Station	No tags
	Bus	2:40pm	Harrisburg Bus Station	12h 20m	3:00am	Downtown Transit Center	No tags
Greyhound Lines, Inc. + FlixBus	Bus	8:15pm	Harrisburg Bus Station	17h	1:15pm	Downtown Transit Center	No tags

Next departures for Harrisburg to Indianapolis on November 28
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	7:45pm	Harrisburg Bus Station	14h	9:45am	Indianapolis Bus Station	Cheapest
	Bus	2:05pm	Harrisburg Bus Station	12h 10m	2:15am	Indianapolis Bus Station	Fastest
	Bus	2:30am	Harrisburg Bus Station	16h 10m	6:40pm	Indianapolis Bus Station	No tags
	Bus	2:40pm	Harrisburg Bus Station	12h 20m	3:00am	Downtown Transit Center	No tags
Greyhound Lines, Inc. + FlixBus	Bus	8:15pm	Harrisburg Bus Station	17h	1:15pm	Downtown Transit Center	No tags

Last refresh of the prices: Yesterday at 5:45 PM EST.

Compare 2 ways to go from Harrisburg to Indianapolis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 14 hours, and with fares starting at just $102, it presents an excellent value for a comfortable ride.

8bus per day

14hAverage Duration

793 kmDistance

20kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$102 - $543	Average Duration14h	CO₂ emissions 20kg CO₂e
Train	Average Price$231 - $974	Average Duration1d 9h	CO₂ emissions 72kg CO₂e

Where are the popular stops in Harrisburg and Indianapolis?

Stops in Harrisburg

A
Harrisburg Bieber Greyhound Station
411 Market St, Harrisburg, PA 17101

Stops in Indianapolis

A
Greyhound Amtrak Station
350 S Illinois St, Indianapolis, IN 46225
Visit page

Compare bus companies

Greyhound

3.5/587,396 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

FlixBus

3.5/511,446 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about travelling from Harrisburg to Indianapolis by bus

What is the travel distance from Harrisburg to Indianapolis?
The distance between Harrisburg and Indianapolis is around 793 km (492 miles).
What are the departure and arrival locations for buses traveling from Harrisburg to Indianapolis?
Buses traveling this route start their trip at Harrisburg Bieber Greyhound Station, in Harrisburg, and end it at Greyhound Amtrak Station, in Indianapolis.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-24

$162

11-25

$162

Today

$156

11-27

No data

11-28

$139

11-29

$194

11-30

$263

12-01

No data

The cheapest trip from Harrisburg to Indianapolis was searched and found on Nov 28, 2025 with a price of $139

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to Indianapolis, as early as possible.

You can expect to pay from $139 to $533 for a bus ticket from Harrisburg to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $139 which is on 2025-11-28.