Next departures for Florence to Lyon on November 19
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Florence (Villa Costanza)
Perrache
Cheapest
Bus
Florence (Villa Costanza)
Perrache
Fastest
Bus
Scandicci - parcheggio scambiatore Villa Costanza
de Perrache - Galerie A
No tags
Bus
Florence (Villa Costanza)
Aéroport LYS
No tags
Bus
Terminal Bus Villa Constanza
Lyon Lyon Perrache Bus Station
No tags
Next departures for Florence to Lyon on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal Bus Villa Constanza
Lyon Lyon Perrache Bus Station
Cheapest
Bus
Florence (Villa Costanza)
Perrache
Fastest
Bus
Florence (Villa Costanza)
Aéroport LYS
No tags
Bus
Terminal Bus Villa Constanza
Lyon Lyon Perrache Bus Station
No tags
Bus
Florence (Villa Costanza)
Aéroport LYS
No tags
Next departures for Florence to Lyon on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal Bus Villa Constanza
Lyon Lyon Perrache Bus Station
Cheapest
Bus
Florence (Villa Costanza)
Perrache
Fastest
Bus
Florence (Villa Costanza)
Aéroport LYS
No tags
Bus
Terminal Bus Villa Constanza
Lyon Lyon Perrache Bus Station
No tags
Bus
Florence (Villa Costanza)
Aéroport LYS
No tags
Last refresh of the prices: Yesterday at 8:42 PM CET.
Compare 3 ways to go from Florence to Lyon
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as the good way to reach Lyon. The journey takes about 8 hours 40 minutes and with fares starting at just $76, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 944 reviews, the company was rated 3.8 stars on Busbud. Travelers were especially satisfied with the ticket access and the temperature but often complained with the timeliness. Itabus ticket prices on this trip start at $22
Based on 11138 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the ticket access and the staff but often complained with the wifi. BlaBlaCar Bus ticket prices on this trip start at $25
Based on 1057 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the departure location and the value for money but often complained with the wifi. RegioJet ticket prices on this trip start at $144
Frequently asked questions about traveling from Florence to Lyon by bus
How far is Florence from Lyon?
About 343 miles (552 km) separate Florence and Lyon.
What are the departure and arrival stations when taking the bus from Florence to Lyon?
Most of the buses traveling from Florence to Lyon leave from Terminal Bus Villa Constanza and arrive at Lyon Airport. These are the main pick-up and drop-off locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.
What are the best sights and things to do in Lyon?
Once in Lyon, you can start exploring the city and discover its surroundings. The top sights and things to do are Aquarium Grand Lyon, Boat Trips, Opéra de Lyon, Musée d’Art Contemporain and Musée des Tissus.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/17
$46
11/18
$40
Today
$34
11/20
$24
11/21
$33
11/22
$28
11/23
$28
11/24
$28
The cheapest trip from Florence to Lyon was searched and found on Nov 20, 2025 with a price of $24
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence to Lyon, as early as possible.
You can expect to pay from $24 to $155 for a bus ticket from Florence to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at $24 which is on 2025-11-20.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from Florence to Lyon was searched and found on Nov 20, 2025 with a price of $24
