Bus from Florence, SC, US to Charlotte, NC: Tickets & Schedules

Previously seen trips

Next departures for Florence to Charlotte on November 26
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBusBus
Florence, SC
Charlotte (Freedom Dr)No tags
FlixBusBus
Florence, SC
Charlotte (Freedom Dr)No tags
GreyhoundBus
Bus station
Charlotte Bus StationNo tags
FlixBusBus
Florence, SC
Charlotte (Freedom Dr)No tags
FlixBus + Greyhound
Bus
Bus station
Charlotte Bus StationNo tags

Compare 2 ways to go from Florence to Charlotte

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Charlotte. The journey takes about 3 hours and with fares starting at just $24, it presents an excellent value for a comfortable ride.

1bus per day
3hAverage Duration
95 milesDistance
4kgCO₂ emissions
Average Price$24 - $88Average Duration3h
4kg CO₂e
Average Price$71 - $1,003Average Duration15h 36m
14kg CO₂e

Frequently asked questions about traveling from Florence, SC, US to Charlotte, NC by bus

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/24
No data
11/25
$30
Today
No data
11/27
No data
11/28
No data
11/29
No data
11/30
No data
12/01
No data
busbud logoThe cheapest trip from Florence, SC, US to Charlotte, NC was searched and found on Nov 25, 2025 with a price of $30

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Charlotte, NC, as early as possible.

What's the cheapest way to go from Florence, SC, US to Charlotte, NC?

busbud logoThe bus is the cheapest travel choice for this destination

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