How far is Chicago from Syracuse?

Chicago and Syracuse are 592 miles (954 km) apart.

What are the departure and arrival stations when taking the bus from Chicago to Syracuse?

Most of the buses traveling from Chicago to Syracuse leave from Downtown Greyhound Station and arrive at Regional Transportation Center. These are the primary departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.

What are the best sights and things to do in Syracuse?

Once in Syracuse, you can start exploring the city and discover its surroundings. The top sights and things to do are Webster Pond, NBT Bank Stadium, WonderWorks, Oncenter War Memorial Arena and Onondaga Lake Park.

Bus Chicago to Syracuse from $77 | Refundable Tickets

Next bus departures

Next departures for Chicago to Syracuse on November 25
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	7:15pm	Downtown Greyhound Station	1d	8:25pm	Syracuse (Regional Transportation Center)	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	7:40pm	Chicago 95Th & Dan Ryan	23h 45m	8:25pm	Syracuse (Regional Transportation Center)	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	10:00am	537-517 W. Jackson Blvd	1d 4h	3:15pm	Syracuse (Regional Transportation Center)	No tags

Next departures for Chicago to Syracuse on November 26
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	7:15pm	Downtown Greyhound Station	1d	8:25pm	Syracuse (Regional Transportation Center)	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	7:40pm	Chicago 95Th & Dan Ryan	23h 45m	8:25pm	Syracuse (Regional Transportation Center)	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	10:00am	537-517 W. Jackson Blvd	1d 4h	3:15pm	Syracuse (Regional Transportation Center)	No tags

Next departures for Chicago to Syracuse on November 27
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	7:40pm	Chicago 95Th & Dan Ryan	23h 45m	8:25pm	Syracuse (Regional Transportation Center)	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	7:15pm	Downtown Greyhound Station	1d	8:25pm	Syracuse (Regional Transportation Center)	No tags
Greyhound Lines, Inc. + FlixBus	Bus	10:00am	537-517 W. Jackson Blvd	1d 4h	3:15pm	Syracuse (Regional Transportation Center)	No tags

Next departures for Chicago to Syracuse on November 28
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	7:40pm	Chicago 95Th & Dan Ryan	23h 40m	8:20pm	Syracuse (Regional Transportation Center)	CheapestFastest
	Bus	7:15pm	Downtown Greyhound Station	1d	8:20pm	Syracuse (Regional Transportation Center)	No tags
Greyhound Lines, Inc. + FlixBus	Bus	10:00am	537-517 W. Jackson Blvd	1d 4h	3:15pm	Syracuse (Regional Transportation Center)	No tags

Next departures for Chicago to Syracuse on November 29
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
FlixBus + Greyhound Lines, Inc.	Bus	7:15pm	Downtown Greyhound Station	1d	8:25pm	Syracuse (Regional Transportation Center)	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	7:40pm	Chicago 95Th & Dan Ryan	23h 45m	8:25pm	Syracuse (Regional Transportation Center)	Fastest

Next departures for Chicago to Syracuse on November 30
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	7:40pm	Chicago 95Th & Dan Ryan	23h 45m	8:25pm	Syracuse (Regional Transportation Center)	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	7:15pm	Downtown Greyhound Station	1d	8:25pm	Syracuse (Regional Transportation Center)	No tags
Greyhound Lines, Inc. + FlixBus	Bus	10:00am	537-517 W. Jackson Blvd	1d 4h	3:15pm	Syracuse (Regional Transportation Center)	No tags

Next departures for Chicago to Syracuse on December 1
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
FlixBus + Greyhound Lines, Inc.	Bus	7:40pm	Chicago 95Th & Dan Ryan	23h 45m	8:25pm	Syracuse (Regional Transportation Center)	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	7:15pm	Downtown Greyhound Station	1d	8:25pm	Syracuse (Regional Transportation Center)	No tags

Next departures for Chicago to Syracuse on December 2
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	6:00pm	Downtown Greyhound Station	1d 1h	8:25pm	Syracuse (Regional Transportation Center)	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	6:40pm	Chicago 95Th & Dan Ryan	1d	8:25pm	Syracuse (Regional Transportation Center)	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	10:00am	537-517 W. Jackson Blvd	1d 4h	3:15pm	Syracuse (Regional Transportation Center)	No tags

Last refresh of the prices: Yesterday at 9:47 PM CST.

Compare 2 ways to go from Chicago to Syracuse

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Syracuse. The journey takes about 12 hours 58 minutes and with fares starting at just $60, it presents an excellent value for a comfortable ride.

1train per day

12h 58mAverage Duration

589 milesDistance

86kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$73 - $407	Average Duration1d	CO₂ emissions 24kg CO₂e
Train	Average Price$60 - $215	Average Duration12h 58m	CO₂ emissions 86kg CO₂e

Where are the popular stops in Chicago and Syracuse?

Stops in Chicago

A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA
Visit page
B
Chicago O'Hare International Airport
Visit page
C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA
D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA
E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA
F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA

Stops in Syracuse

A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208
Visit page
B
Syracuse Airport
Visit page
C
Syracuse University
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
Visit page
D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA
E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA
F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA

Compare bus companies

FlixBus

3.5/511,439 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,393 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Chicago to Syracuse, US by bus

How far is Chicago from Syracuse?
What are the departure and arrival stations when taking the bus from Chicago to Syracuse?
What are the best sights and things to do in Syracuse?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/22

No data

11/23

$96

Today

$98

11/25

$98

11/26

$103

11/27

No data

11/28

$199

11/29

$134

The cheapest trip from Chicago to Syracuse, US was searched and found on Nov 23, 2025 with a price of $96

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Syracuse, US, as early as possible.

You can expect to pay from $96 to $227 for a bus ticket from Chicago to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at $98 which is on 2025-11-25.