Next departures from Chicago to Syracuse on 23 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Downtown Greyhound Station
Syracuse (Regional Transportation Center)
Cheapest
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
Syracuse (Regional Transportation Center)
Fastest
Next departures from Chicago to Syracuse on 24 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Downtown Greyhound Station
Syracuse (Regional Transportation Center)
Cheapest
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
Syracuse (Regional Transportation Center)
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
537-517 W. Jackson Blvd
Syracuse (Regional Transportation Center)
No tags
Next departures from Chicago to Syracuse on 25 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Downtown Greyhound Station
Syracuse (Regional Transportation Center)
Cheapest
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
Syracuse (Regional Transportation Center)
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
537-517 W. Jackson Blvd
Syracuse (Regional Transportation Center)
No tags
Next departures from Chicago to Syracuse on 26 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Downtown Greyhound Station
Syracuse (Regional Transportation Center)
Cheapest
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
Syracuse (Regional Transportation Center)
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
537-517 W. Jackson Blvd
Syracuse (Regional Transportation Center)
No tags
Next departures from Chicago to Syracuse on 27 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
Syracuse (Regional Transportation Center)
CheapestFastest
FlixBus + Greyhound Lines, Inc.
Bus
Downtown Greyhound Station
Syracuse (Regional Transportation Center)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
537-517 W. Jackson Blvd
Syracuse (Regional Transportation Center)
No tags
Next departures from Chicago to Syracuse on 28 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Chicago 95Th & Dan Ryan
Syracuse (Regional Transportation Center)
CheapestFastest
Bus
Downtown Greyhound Station
Syracuse (Regional Transportation Center)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
537-517 W. Jackson Blvd
Syracuse (Regional Transportation Center)
No tags
Next departures from Chicago to Syracuse on 29 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Downtown Greyhound Station
Syracuse (Regional Transportation Center)
Cheapest
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
Syracuse (Regional Transportation Center)
Fastest
Next departures from Chicago to Syracuse on 30 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
Syracuse (Regional Transportation Center)
CheapestFastest
FlixBus + Greyhound Lines, Inc.
Bus
Downtown Greyhound Station
Syracuse (Regional Transportation Center)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
537-517 W. Jackson Blvd
Syracuse (Regional Transportation Center)
No tags
Last refresh of the prices: Yesterday at 09:14 CST.
Compare 2 ways to travel from Chicago to Syracuse
We recommend taking the train
Among the sustainable travel choices, the train stands out as a good way to reach Syracuse. The journey takes about 12 hours 58 minutes and with fares starting at just £47, it presents an excellent value for a comfortable ride.
Based on 11411 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at £127
Based on 87391 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at £66
Frequently asked questions about travelling by bus from Chicago to Syracuse, US
What's the distance between Chicago and Syracuse by coach?
The journey from Chicago to Syracuse by coach covers an approximate distance of 592 miles (954 km).
How can I travel from Chicago to Syracuse avoiding air travel?
To travel from Chicago to Syracuse without flying, you can take the coaches. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
21/11
No data
22/11
No data
Today
£76
24/11
£77
25/11
£77
26/11
£81
27/11
No data
28/11
£179
The cheapest trip from Chicago to Syracuse, US was searched and found on 23 Nov 2025 with a price of £76
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Syracuse, US as early as possible.
You can expect to pay from £76 to £186 for a bus ticket from Chicago to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at £77, which is on 2025-11-24.
The cheapest trip from Chicago to Syracuse, US was searched and found on 23 Nov 2025 with a price of £76
