Bus Tickets from Chicago to La Crosse, WI

Next departures

Next departures for Chicago to La Crosse on November 4
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Jefferson Lines
    		Chicago (Bus Station)
    		La Crosse MTU Transit CenterCheapestFastest
    Jefferson Lines
      		Chicago (Bus Station)
      		632 17th Street NorthNo tags

      Last refresh of the prices: Yesterday at 8:35 PM CST.

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      Get from Chicago to La Crosse

      This route is served by train only

      The journey takes about 5 hours 1 minute and with fares starting at just $34, it presents an excellent value for a comfortable ride.

      3train per day
      5h 1mAverage Duration
      227 milesDistance
      33kgCO₂ emissions

      Frequently asked questions for your trip Chicago - La Crosse, WI

      Find cheapest prices for buses

      Price is for a one-way ticket for one passenger and based on past searches.

      Best price found
      11/01
      No data
      11/02
      $179
      Today
      No data
      11/04
      $179
      11/05
      No data
      11/06
      No data
      11/07
      No data
      11/08
      No data
      busbud logoThe cheapest trip from Chicago to La Crosse, WI was searched and found on Nov 2, 2025 with a price of $179

      To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to La Crosse, WI, as early as possible.

      You can expect to pay from $179 to $179 for a bus ticket from Chicago to La Crosse, WI based on the last 2 days. You can expect to find the cheapest price for the trip at $179 which is on 2025-11-04.

      About Bus Travel

      Bus Travel Tips

      Meet and talk to locals at the bus stations while traveling from Chicago to La Crosse.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

      Start sightseeing the minute your bus leaves the station. If you're on the night bus from Chicago to La Crosse, get comfy and count the stars.

      Buses are energy-efficient. Carrying a passenger over 100 kms by bus only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Chicago to La Crosse.

      Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Chicago to La Crosse.

      Did you know?

      The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

      Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

      The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

      Will you be returning to Chicago by bus?

      Bus from La Crosse, WI to Chicago

      You can also go to La Crosse, WI by train

      Train from Chicago to La Crosse, WI

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