Bus from Chicago to Harrisburg: Tickets & Schedules

Next bus departures

Next departures for Chicago to Harrisburg on November 29
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Downtown Greyhound Station
Harrisburg Bus StationCheapest
Greyhound Lines, Inc.Bus
Downtown Greyhound Station
Harrisburg Bus StationFastest
Greyhound Lines, Inc.Bus
Downtown Greyhound Station
Harrisburg Bus StationNo tags
FlixBusBus
Downtown Greyhound Station
Harrisburg Bus StationNo tags
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
Harrisburg Bus StationNo tags

Last refresh of the prices: Yesterday at 5:28 PM CST.

Compare 2 ways to go from Chicago to Harrisburg

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Harrisburg. The journey takes about 16 hours 15 minutes and with fares starting at just $79, it presents an excellent value for a comfortable ride.

9bus per day
16h 15mAverage Duration
571 milesDistance
23kgCO₂ emissions
Average Price$79 - $313Average Duration16h 15m
23kg CO₂e
Average Price$102 - $1,283Average Duration17h 15m
84kg CO₂e

Frequently asked questions about traveling from Chicago to Harrisburg by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Chicago to Harrisburg?

    The cheapest bus tickets from Chicago to Harrisburg start from $79. The average price for this route is around $130. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Chicago to Harrisburg?

    The average bus trip duration from Chicago to Harrisburg is 16h 15m, covering a distance of 571 miles (920 km). The quickest bus can get you there in 15h 15m and is operated by Greyhound.

  3. Which bus companies service the Chicago to Harrisburg route?

    Several major bus companies operate on this route with 9 buses available per day, including services from Greyhound, FlixBus.

  4. What is the earliest and latest departure time for the bus from Chicago to Harrisburg?

    The earliest bus departs from Chicago to Harrisburg at 4:45am. And the latest bus departs at 11:40pm.

  5. What are the CO₂ emissions for the bus trip from Chicago to Harrisburg?

    A bus trip from Chicago to Harrisburg generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Chicago to Harrisburg?

    According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.

  7. Which bus company has the best Wi-Fi from Chicago to Harrisburg?

    Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company has the most timely service from Chicago to Harrisburg?

    According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Chicago to Harrisburg?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/26
$155
11/27
$124
Today
$138
11/29
$208
11/30
$191
12/01
$104
12/02
$104
12/03
$84
busbud logoThe cheapest trip from Chicago to Harrisburg was searched and found on Dec 3, 2025 with a price of $84

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Harrisburg, as early as possible.

You can expect to pay from $84 to $293 for a bus ticket from Chicago to Harrisburg based on the last 2 days. You can expect to find the cheapest price for the trip at $84 which is on 2025-12-03.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Chicago to Harrisburg?

busbud logoThe bus is the cheapest travel choice for this destination

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