Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Chicago 95Th & Dan Ryan | Harrisburg Bus Station | Cheapest | ||||
 | Bus | Downtown Greyhound Station | Harrisburg Bus Station | Fastest | ||||
| Bus | Downtown Greyhound Station | Harrisburg Bus Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Downtown Greyhound Station | Harrisburg Bus Station | No tags | ||||
| Bus | 537-517 W. Jackson Blvd | Harrisburg Bus Station | No tags |
Last refresh of the prices: Yesterday at 08:58 CST.
Compare 2 ways to travel from Chicago to Harrisburg
Among the sustainable travel choices, the bus stands out as a good way to reach Harrisburg. The journey takes about 16 hours 15 minutes and with fares starting at just £61, it presents an excellent value for a comfortable ride.
Where are the popular stops in Chicago and Harrisburg?
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Stops in Harrisburg
- A
Harrisburg Bieber Greyhound Station
411 Market St, Harrisburg, PA 17101
Compare bus companies
Frequently asked questions about travelling by bus from Chicago to Harrisburg
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Chicago to Harrisburg?
The cheapest coach tickets from Chicago to Harrisburg start from £61. The average price for this route is around £101. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Chicago to Harrisburg?
The average bus journey time from Chicago to Harrisburg is 16h 15m, covering a distance of 571 miles. The fastest bus can take you there in 15h 15m and is operated by Greyhound.
Which bus companies service the Chicago to Harrisburg route?
What is the earliest and latest departure time for the bus from Chicago to Harrisburg?
The earliest bus departs from Chicago to Harrisburg at 04:45. And the latest bus departs at 23:40.
What are the CO₂ emissions for the bus trip from Chicago to Harrisburg?
A bus journey from Chicago to Harrisburg produces an estimated 23 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Chicago to Harrisburg?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which company has the best Wi-Fi from Chicago to Harrisburg?
Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Chicago to Harrisburg?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Chicago to Harrisburg?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to Harrisburg was searched and found on 4 Dec 2025 with a price of £64To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Harrisburg as early as possible.
You can expect to pay from £64 to £258 for a bus ticket from Chicago to Harrisburg based on the last 2 days. You can expect to find the cheapest price for the trip at £64, which is on 2025-12-04.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Chicago to Harrisburg?
The bus is the cheapest travel choice for this destination
