How much is the bus ticket from Charleston to Chicago?

The cheapest bus tickets from Charleston to Chicago start from $106. The average price for this route is around $153. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Charleston to Chicago?

The average bus trip duration from Charleston to Chicago is 1d 5h, covering a distance of 748 miles (1207 km). The quickest bus can get you there in 1d 5h and is operated by Greyhound .

Which bus companies service the Charleston to Chicago route?

Several major bus companies operate on this route with 3 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from Charleston to Chicago?

The earliest bus departs from Charleston to Chicago at 11:15am. And the latest bus departs at 11:15am.

What are the CO₂ emissions for the bus trip from Charleston to Chicago?

A bus trip from Charleston to Chicago generates an estimated 30 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Charleston to Chicago?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87435 reviews.

Which bus company has the best Wi-Fi from Charleston to Chicago?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Charleston to Chicago?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Charleston to Chicago?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Charleston to Chicago from $129 | Refundable Tickets

Next bus departures

Next departures for Charleston to Chicago on January 1
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	11:15am	4565 Gaynor Ave, North Charleston	1d 5h	3:55pm	Chicago 95Th & Dan Ryan	Cheapest
	Bus	11:15am	4565 Gaynor Ave, North Charleston	1d 5h	3:15pm	Downtown Greyhound Station	Fastest
	Bus	11:15am	4565 Gaynor Ave, North Charleston	1d 21h	8:00am	537-517 W. Jackson Blvd	No tags

Next departures for Charleston to Chicago on January 2
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	11:15am	4565 Gaynor Ave, North Charleston	1d 5h	3:55pm	Chicago 95Th & Dan Ryan	Cheapest
	Bus	11:15am	4565 Gaynor Ave, North Charleston	1d 5h	3:15pm	Downtown Greyhound Station	Fastest
	Bus	11:15am	4565 Gaynor Ave, North Charleston	1d 21h	8:00am	537-517 W. Jackson Blvd	No tags

Last refresh of the prices: Yesterday at 10:20 AM EST.

Compare 2 ways to go from Charleston to Chicago

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 1 day, 5 hours 40 minutes and with fares starting at just $106, it presents an excellent value for a comfortable ride.

3bus per day

1d 5hAverage Duration

748 milesDistance

30kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$106 - $434	Average Duration1d 5h	CO₂ emissions 30kg CO₂e
Train	Average Price$231 - $3,744	Average Duration1d 13h	CO₂ emissions 110kg CO₂e

Where are the popular stops in Charleston and Chicago?

Stops in Charleston

A
Charleston Bus Station
3610 Dorchester Rd, North Charleston, SC 29405

Stops in Chicago

A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA
Visit page
B
Chicago O'Hare International Airport
Visit page
C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA
D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA
E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA
F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA

Compare bus companies

Greyhound

3.5/587,468 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,838 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Charleston, SC, US to Chicago by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Charleston to Chicago?
The cheapest bus tickets from Charleston to Chicago start from $106. The average price for this route is around $153. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Charleston to Chicago?
The average bus trip duration from Charleston to Chicago is 1d 5h, covering a distance of 748 miles (1207 km). The quickest bus can get you there in 1d 5h and is operated by Greyhound.
Which bus companies service the Charleston to Chicago route?
Several major bus companies operate on this route with 3 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Charleston to Chicago?
The earliest bus departs from Charleston to Chicago at 11:15am. And the latest bus departs at 11:15am.
What are the CO₂ emissions for the bus trip from Charleston to Chicago?
A bus trip from Charleston to Chicago generates an estimated 30 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Charleston to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87435 reviews.
Which bus company has the best Wi-Fi from Charleston to Chicago?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Charleston to Chicago?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Charleston to Chicago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

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Today

$245

The cheapest trip from Charleston, SC, US to Chicago was searched and found on Jan 1, 2026 with a price of $245

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, SC, US to Chicago, as early as possible.

You can expect to pay from $245 to $416 for a bus ticket from Charleston, SC, US to Chicago based on the last 0 days. You can expect to find the cheapest price for the trip at $275 which is on 2026-01-02.