Bus from Boston, MA, US to Indianapolis: Tickets & Schedules

Next bus departures

Next departures for Boston to Indianapolis on November 30
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.Bus
Boston (South Station)
Indianapolis Bus StationCheapestFastest
Greyhound Lines, Inc.Bus
Boston (South Station)
Indianapolis Bus StationNo tags
Greyhound Lines, Inc. + FlixBus
Bus
Boston (South Station)
Downtown Transit CenterNo tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
Indianapolis Bus StationNo tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
Indianapolis Bus StationNo tags

Last refresh of the prices: Yesterday at 7:10 PM EST.

Compare 2 ways to go from Boston to Indianapolis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Indianapolis. The journey takes about 1 day, 5 hours 5 minutes and with fares starting at just $111, it presents an excellent value for a comfortable ride.

17bus per day
1d 5hAverage Duration
801 milesDistance
32kgCO₂ emissions
Average Price$111 - $463Average Duration1d 5h
32kg CO₂e
Average Price$120 - $886Average Duration1d 10h
118kg CO₂e

Frequently asked questions about traveling from Boston, MA, US to Indianapolis by bus

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/24
$222
11/25
$274
Today
$274
11/27
$194
11/28
No data
11/29
$296
11/30
$352
12/01
$242
busbud logoThe cheapest trip from Boston, MA, US to Indianapolis was searched and found on Nov 27, 2025 with a price of $194

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Indianapolis, as early as possible.

You can expect to pay from $194 to $428 for a bus ticket from Boston, MA, US to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $194 which is on 2025-11-27.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Boston, MA, US to Indianapolis?

busbud logoThe bus is the cheapest travel choice for this destination

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