Next departures for Boston to Indianapolis on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Brookline
Downtown Transit Center
Cheapest
Bus
Boston (South Station)
Indianapolis Bus Station
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Boston (South Station)
Downtown Transit Center
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Boston (South Station)
Indianapolis Northeast
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
Indianapolis Bus Station
No tags
Next departures for Boston to Indianapolis on November 30
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Boston (South Station)
Indianapolis Bus Station
CheapestFastest
Bus
Boston (South Station)
Indianapolis Bus Station
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Boston (South Station)
Downtown Transit Center
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
Indianapolis Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
Indianapolis Bus Station
No tags
Next departures for Boston to Indianapolis on December 1
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
Indianapolis Bus Station
Cheapest
Bus
Boston (South Station)
Indianapolis Bus Station
Fastest
Bus
Boston (South Station)
Indianapolis Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
Indianapolis Bus Station
No tags
Bus
Boston (South Station)
Indianapolis Bus Station
No tags
Last refresh of the prices: Yesterday at 7:10 PM EST.
Compare 2 ways to go from Boston to Indianapolis
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Indianapolis. The journey takes about 1 day, 5 hours 5 minutes and with fares starting at just $111, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Boston, MA, US to Indianapolis by bus
What is the travel distance from Boston to Indianapolis?
Boston and Indianapolis are 805 miles (1298 km) apart.
What are the departure and arrival stations when taking the bus from Boston to Indianapolis?
The majority of buses traveling from Boston to Indianapolis start their journey at Back Bay Station and wind up at Greyhound Amtrak Station. These are the most popular pick-up and drop-off locations on this route, but you could find others that could be a better fit for your travel plans.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/24
$222
11/25
$274
Today
$274
11/27
$194
11/28
No data
11/29
$296
11/30
$352
12/01
$242
The cheapest trip from Boston, MA, US to Indianapolis was searched and found on Nov 27, 2025 with a price of $194
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Indianapolis, as early as possible.
You can expect to pay from $194 to $428 for a bus ticket from Boston, MA, US to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $194 which is on 2025-11-27.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Boston, MA, US to Indianapolis?
The bus is the cheapest travel choice for this destination