Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Boston (South Station) | Downtown Transit Center | Cheapest | ||||
 | Bus | Boston (South Station) | Indianapolis Bus Station | Fastest | ||||
| Bus | Boston (South Station) | Indianapolis Bus Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Boston (South Station) | Indianapolis Bus Station | No tags | ||||
| Bus | Brookline | Downtown Transit Center | No tags |
Last refresh of the prices: Yesterday at 7:21 PM EST.
Compare 2 ways to go from Boston to Indianapolis
Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 1 day, 4 hours 25 minutes, and with fares starting at just $149, it presents an excellent value for a comfortable ride.
Where are the popular stops in Boston and Indianapolis?
Stops in Boston
- A145 Dartmouth St, Boston, MA 02116, USA
- B100 Legends Way, Boston, MA 02114, USA
- C700 Atlantic Ave, Boston, MA 02205, USA
- D
Copley Square
115-127 St James Ave, Boston, MA 02116, USA - E
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA - F
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA
Compare bus companies
Frequently asked questions about travelling from Boston, MA, US to Indianapolis by bus
What is the travel distance from Boston to Indianapolis?
The distance between Boston and Indianapolis is approximately 1298 km (805 miles).
What are the departure and arrival locations for buses traveling from Boston to Indianapolis?
Buses departing from Back Bay Station in Boston will take you to Greyhound Amtrak Station in Indianapolis.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Boston, MA, US to Indianapolis was searched and found on Nov 22, 2025 with a price of $250To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Indianapolis, as early as possible.
You can expect to pay from $250 to $470 for a bus ticket from Boston, MA, US to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $250 which is on 2025-11-22.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Boston, MA, US to Indianapolis?
The bus is the cheapest travel choice for this destination
