Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Big Spring (Shell) | San Ysidro Bus terminal | CheapestFastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Big Spring (Shell) | San Ysidro Bus terminal | No tags |
Last refresh of the prices: Yesterday at 9:49 PM CST.
Get from Big Spring to San Ysidro
The journey takes about 1 day, 6 hours 40 minutes and with fares starting at just $126, it presents an excellent value for a comfortable ride.
Where are the popular stops in Big Spring and San Ysidro?
Stops in Big Spring
- A
Big Spring Bus Station
301-399 I-20BL, Big Spring, TX 79720, USA - B
Big Spring Bus Stop
400-498 E 20th St, Big Spring, TX 79720, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Big Spring to San Ysidro, CA by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Big Spring to San Ysidro?
The cheapest bus tickets from Big Spring to San Ysidro start from $126. The average price for this route is around $151. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Big Spring to San Ysidro?
The average bus trip duration from Big Spring to San Ysidro is 1d 6h, covering a distance of 903 miles (1456 km). The quickest bus can get you there in 1d and is operated by Greyhound.
Which bus companies service the Big Spring to San Ysidro route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Big Spring to San Ysidro?
The earliest bus departs from Big Spring to San Ysidro at 5:55am. And the latest bus departs at 7:40pm.
What are the CO₂ emissions for the bus trip from Big Spring to San Ysidro?
A bus trip from Big Spring to San Ysidro generates an estimated 36 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Big Spring to San Ysidro, CA was searched and found on Dec 26, 2025 with a price of $120To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Big Spring to San Ysidro, CA, as early as possible.
You can expect to pay from $120 to $167 for a bus ticket from Big Spring to San Ysidro, CA based on the last 2 days. You can expect to find the cheapest price for the trip at $120 which is on 2025-12-26.
