Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Brussels South/Midi Train Station | Hlavní nádraží | CheapestFastest | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | No tags | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | No tags | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | No tags | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | No tags |
Last refresh of the prices: Today at 9:25 AM CET.
Compare 2 ways to travel from Brussels to Prague
Among the sustainable travel choices, the Train stands out as a good way to reach Prague. The journey takes about 15 hours 29 minutes and with fares starting at just R 1 509, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Brussels and Prague?
Brussels
- ARue de France 85, 1060 Saint-Gilles, Belgium
- BBoulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
- C
Bruxelles / Brussels Central
Brussel-Centraal, Carrefour de l'Europe, 1000 Bruxelles, Belgium
Prague
- A300/8 Wilsonova, 110 00 Praha, Czechia
- B
Praha hl.n
Prague Main Railway Station, 120 00 Praha-Praha 2, Czechia - CKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- DAviatická, 161 08, Praha 6, Czechia
- EChlumecká, 198 00 Praha 20, Czech Republic
- FTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
Train Companies
Based on 8 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the power outlets and the ticket access but often complained with the timeliness. Deutsche Bahn ticket prices on this trip start at R 3 911
Frequently asked questions about travelling from Brussels to Prague by train
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the train ticket from Brussels to Prague?
The cheapest train tickets from Brussels to Prague start from R 1 509. The average price for this train route is around R 2 175. Busbud recommends booking your tickets in advance for a better chance to secure the lowest possible price.
How long is the train journey from Brussels to Prague?
The average train journey time from Brussels to Prague is 15h 29m, covering a distance of 718 km. The quickest train can get you there in 12h 47m and is operated by Deutsche Bahn.
Which train operators serve the Brussels to Prague route?
Several major train operators run on this route, with 1 trains available per day.
What are the earliest and latest departure times for the train from Brussels to Prague?
The earliest train from Brussels to Prague departs at 18:22. And the latest train departs at 20:24.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Brussels to Prague was searched and found on 28 Jan 2026 with a price of R 3 387To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Brussels to Prague as early as possible.
You can expect to pay from R 3 387 to R 11 965 for a train ticket from Brussels to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at R 3 387, which is on 2026-01-28.
