Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Brussels South/Midi Train Station | Hlavní nádraží | CheapestFastest | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | No tags | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | No tags | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | No tags | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | No tags |
Last refresh of the prices: Today at 9:25 AM CET.
Compare 2 ways to go from Brussels to Prague
Among the sustainable travel choices, the Train stands out as a good way to reach Prague. The journey takes about 15 hours 29 minutes, and with fares starting at just $129, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Brussels and Prague?
Brussels
- ARue de France 85, 1060 Saint-Gilles, Belgium
- BBoulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
- C
Bruxelles / Brussels Central
Brussel-Centraal, Carrefour de l'Europe, 1000 Bruxelles, Belgium
Prague
- A300/8 Wilsonova, 110 00 Praha, Czechia
- B
Praha hl.n
Prague Main Railway Station, 120 00 Praha-Praha 2, Czechia - CKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- DAviatická, 161 08, Praha 6, Czechia
- EChlumecká, 198 00 Praha 20, Czech Republic
- FTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
Train companies
Based on 8 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the power outlets and the ticket access but often complained with the timeliness. Deutsche Bahn ticket prices on this trip start at $334
Frequently asked questions about travelling from Brussels to Prague by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Brussels to Prague?
The cheapest train tickets from Brussels to Prague start at $129. The average price for this train route is around $186. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.
How long is the train ride from Brussels to Prague?
The average train trip from Brussels to Prague takes 15h 29m and covers 718 km. The quickest train gets you there in 12h 47m and is operated by Deutsche Bahn.
Which train operators serve the Brussels to Prague route?
Several major train operators serve this route, with 1 trains available per day.
What are the earliest and latest departure times for the train from Brussels to Prague?
The earliest train from Brussels to Prague departs at 6:22pm. The latest train departs at 8:24pm.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Brussels to Prague was searched and found on Jan 28, 2026 with a price of $289To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Brussels to Prague, as early as possible.
You can expect to pay from $289 to $1,021 for a train ticket from Brussels to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $289 which is on 2026-01-28.
