Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Winston Salem Greyhound Bus Station | Harrisburg Bus Station | CheapestFastest | ||||
 | Bus | Winston Salem Greyhound Bus Station | Harrisburg Bus Station | No tags |
Last refresh of the prices: Yesterday at 3:17 AM EST.
Get from Winston-Salem to Harrisburg
The journey takes about 19 hours 40 minutes, and with fares starting at just R 1 746, it presents an excellent value for a comfortable ride.
Where are the popular stops in Winston-Salem and Harrisburg?
Stops in Winston-Salem
- A
Winston Salem Greyhound Bus Station
100 W 5th St, Winston Salem, NC 27101 - B
E Sprague St
841 E Sprague St, Winston-Salem, NC 27107, USA - C
Winston-Salem Bus Stop
2500 Old Lexington Rd, Winston-Salem, NC 27107, USA - D
1237 Silas Creek Pkwy
1237 Silas Creek Pkwy., Winston-Salem, NC 27127 (Hong Kong King Buffet)
Compare bus companies
Based on 87515 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 2 568
Frequently asked questions about travelling from Winston-Salem to Harrisburg by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Winston-Salem to Harrisburg?
The cheapest bus tickets from Winston-Salem to Harrisburg start at R 1 746. The average price for this route is around R 2 568. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Winston-Salem to Harrisburg?
The average bus journey time from Winston-Salem to Harrisburg is 19h 40m, covering a distance of 549 km. The fastest bus gets you there in 19h 15m and is operated by Greyhound.
Which bus companies service the Winston-Salem to Harrisburg route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Winston-Salem to Harrisburg?
The earliest bus departs from Winston-Salem to Harrisburg at 07:10. And the latest bus departs at 18:15.
What are the CO₂ emissions for the bus trip from Winston-Salem to Harrisburg?
A bus trip from Winston-Salem to Harrisburg produces an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Winston-Salem to Harrisburg was searched and found on 21 Jan 2026 with a price of R 3 068To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Winston-Salem to Harrisburg as early as possible.
