How much is the bus ticket from Tampa to Florence?

The cheapest bus tickets from Tampa to Florence start at R 1 359. The average price for this route is around R 1 814. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

How long is the bus journey from Tampa to Florence?

The average bus journey time from Tampa to Florence is 20h 5m, covering a distance of 727 km. The fastest bus gets you there in 12h 57m and is operated by Amtrak .

Which bus companies service the Tampa to Florence route?

Several major bus companies operate on this route with 7 buses available per day, including services from FlixBus , Amtrak , Greyhound .

What is the earliest and latest departure time for the bus from Tampa to Florence?

The earliest bus departs from Tampa to Florence at 09:30. And the latest bus departs at 22:35.

What are the CO₂ emissions for the bus trip from Tampa to Florence?

A bus trip from Tampa to Florence produces an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

What is the best bus company from Tampa to Florence?

According to Busbud customers, the highest-rated bus company on this route is Amtrak , with an average rating of 4.1 out of 5 stars based on 5627 reviews.

Which bus company has the best Wi-Fi from Tampa to Florence?

Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.

Which bus company offers the most punctual service from Tampa to Florence?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Tampa to Florence?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak , with a cleanliness rating of 4.5 out of 5 stars.

Bus Tampa to Florence from R 1 245 | Refundable Tickets

Next departures

Next departures from Tampa to Florence on 20 December
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	09:30	Tampa Bus Station	14h 35m	00:05	Florence, SC	Cheapest
	10:25	Union Station	12h 57m	23:22	Florence Station	Fastest
	10:25	Union Station	12h 57m	23:22	Florence Station	No tags
FlixBus + Greyhound Lines, Inc.	09:30	Tampa Bus Station	1d 2h	11:45	Bus station	No tags
	22:35	Tampa Bus Station	15h	13:35	Bus station	No tags

Next departures from Tampa to Florence on 24 December
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	22:35	Tampa Bus Station	15h	13:35	Bus station	Cheapest
	10:25	Union Station	12h 57m	23:22	Florence Station	Fastest
	10:25	Union Station	12h 57m	23:22	Florence Station	No tags
FlixBus + Greyhound Lines, Inc.	09:30	Tampa Bus Station	1d 2h	11:45	Bus station	No tags
	09:30	Tampa Bus Station	14h 35m	00:05	Florence, SC	No tags

Last refresh of the prices: Today at 8:46 AM EST.

Compare 2 ways to travel from Tampa to Florence

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 20 hours 5 minutes and with fares starting at just R 1 359, it presents an excellent value for a comfortable ride.

7bus per day

20h 5mAverage duration

727 kmDistance

18kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average priceR 1 359 - R 4 655	Average duration20h 5m	CO₂ emissions 18kg CO₂e
Train	Average priceR 1 247 - R 20 437	Average duration18h	CO₂ emissions 67kg CO₂e

Where are the popular stops in Tampa and Florence?

Stops in Tampa

A
Tampa 13th Avenue Bus Stop (McDonald's)
2101 E 13th Ave (McDonald's), Tampa, FL 33605
B
Tampa USF, FL
3801 USF Holly Drive, Tampa., FL 33620, USA
C
Greyhound Station
610 E Polk St, Tampa, FL 33602, USA
D
E Sligh Ave
11555 E Sligh Ave, Seffner, FL 33584, USA
E
N Marion St & E Laurel St
551 E Laurel St, Tampa, FL 33602, USA
F
Port of Tampa
200-298 FL-60, Tampa, FL 33602, USA

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Compare bus companies

FlixBus

3.5/511 661 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

WiFi2.7

Amtrak

4/55 658 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

WiFi3.6

Greyhound

3.5/587 439 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

WiFi2.4

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from Tampa to Florence, SC, US by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

How much is the bus ticket from Tampa to Florence?
The cheapest bus tickets from Tampa to Florence start at R 1 359. The average price for this route is around R 1 814. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Tampa to Florence?
The average bus journey time from Tampa to Florence is 20h 5m, covering a distance of 727 km. The fastest bus gets you there in 12h 57m and is operated by Amtrak.
Which bus companies service the Tampa to Florence route?
Several major bus companies operate on this route with 7 buses available per day, including services from FlixBus, Amtrak, Greyhound.
What is the earliest and latest departure time for the bus from Tampa to Florence?
The earliest bus departs from Tampa to Florence at 09:30. And the latest bus departs at 22:35.
What are the CO₂ emissions for the bus trip from Tampa to Florence?
A bus trip from Tampa to Florence produces an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Tampa to Florence?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5627 reviews.
Which bus company has the best Wi-Fi from Tampa to Florence?
Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.
Which bus company offers the most punctual service from Tampa to Florence?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Tampa to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

17/12

R 1 339

18/12

R 1 751

Today

R 1 416

20/12

R 3 090

21/12

R 1 477

22/12

No data

23/12

No data

24/12

R 2 163

The cheapest trip from Tampa to Florence, SC, US was searched and found on 17 Dec 2025 with a price of R 1 339

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tampa to Florence, SC, US as early as possible.

You can expect to pay from R 1 339 to R 13 546 for a bus ticket from Tampa to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 477, which is on 2025-12-21.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.