Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Union Station | Florence Station | CheapestFastest | |||||
| Union Station | Florence Station | No tags | |||||
FlixBus + Greyhound Lines, Inc. | Tampa Bus Station | Bus station | No tags | |||||
 | Tampa Bus Station | Bus station | No tags | |||||
FlixBus + Greyhound Lines, Inc. | Tampa Bus Station | Bus station | No tags |
Last refresh of the prices: Today at 7:57 AM EST.
Accepted payments
Compare 2 ways to travel from Tampa to Florence
Among the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 18 hours 15 minutes and with fares starting at just R 1 280, it presents an excellent value for a comfortable ride.
Bus Tampa to Florence, SC, US: Trip Overview
Compare bus companies
Tampa to Florence Bus
Busbud helps you find a bus from Tampa to Florence. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Tampa to Florence.
Whether it is cheap bus tickets or more luxurious buses going to Florence from Tampa, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Tampa and Florence?
Frequently asked questions on the trip Tampa - Florence, SC, US
How much does a bus ticket from Tampa to Florence cost?
The bus ticket price from Tampa to Florence starts at R 1 280. The best way to find cheap bus tickets from Tampa to Florence is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Tampa to Florence?
The average travel time between Tampa and Florence is around 18h 15m, although the fastest bus will take about 14h 35m. This is the time it takes to travel the 747 km that separates the two cities.
How many daily bus connections are there between Tampa and Florence?
The number of buses from Tampa to Florence can differ depending on the day of the week. On average, there are 4 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Tampa to Florence by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Tampa to Florence?
When taking the bus from Tampa to Florence, you can travel comfortably and safely with FlixBus, Amtrak, Greyhound.
What are the departure and arrival stations when taking the bus from Tampa to Florence?
Buses travelling between Tampa and Florence leave from Tampa 13th Avenue Bus Stop (McDonald's) or Tampa USF, FL and arrive at Florence Bus Station, TA Travel Center - Florence.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tampa to Florence, SC, US was searched and found on 03 Nov 2025 with a price of R 1 385To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tampa to Florence, SC, US as early as possible.
You can expect to pay from R 1 385 to R 9 369 for a bus ticket from Tampa to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 672, which is on 2025-11-05.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Tampa and Florence!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Tampa to Florence.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Tampa to Florence.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Tampa to Florence.
Did you know?
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
What's the cheapest way to go from Tampa to Florence, SC, US?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
People from around the world trust Busbud
Popular Buses Connecting Tampa
Buses Leaving from Tampa
- Bus from Tampa to Orlando
- Coach Tampa - Miami
- Bus Tampa - Miami
- Bus from Tampa to Atlanta
- Coach Tampa - Sarasota
- Bus Tampa - Fort Myers
- Bus from Tampa to Dansville
- Coach Tampa - Elko
- Bus Tampa - Grambling
- Bus from Tampa to Washington
- Coach Tampa - Jacksonville
- Bus Tampa - Friona
- Bus from Tampa to Moultrie
- Coach Tampa - Montpelier
- Bus Tampa - Topeka
Buses Going to Tampa
- Bus from Orlando to Tampa
- Coach St. Petersburg - Tampa
- Bus Fort Myers - Tampa
- Bus from Boston to Tampa
- Coach Naples - Tampa
- Bus Jackson - Tampa
- Bus from Lansing to Tampa
- Coach Williams - Tampa
- Bus Madisonville - Tampa
- Bus from Salem to Tampa
- Coach Gallup - Tampa
- Bus Tyler - Tampa
- Bus from Jupiter to Tampa
- Coach Austin - Tampa
- Bus Bartow - Tampa
Popular Buses Connecting Florence
Buses Leaving from Florence
- Bus from Florence to Kansas City
- Coach Florence - Kansas City
- Bus Florence - Oklahoma City
- Bus from Florence to Houston
- Coach Florence - Jackson
- Bus Florence - Montgomery
- Bus from Florence to Anderson
- Coach Florence - Tampa
- Bus Florence - Boston
- Bus from Florence to Madisonville
- Coach Florence - Huntsville
- Bus Florence - Providence
- Bus from Florence to Allentown
- Coach Florence - Easton
- Bus Florence - Austin
Buses Going to Florence
- Bus from Syracuse to Florence
- Coach Manchester - Florence
- Bus Columbus - Florence
- Bus from Columbus to Florence
- Coach Los Angeles - Florence
- Bus Toronto - Florence
- Bus from Raleigh to Florence
- Coach Greenville - Florence
- Bus Portland - Florence
- Bus from Tampa to Florence
- Coach Lewistown - Florence
- Bus Austin - Florence
- Bus from Athens to Florence
- Coach Albuquerque - Florence
- Bus Huntsville - Florence
Popular routes in this country
- Bus from Buffalo to Niagara Falls
- Coach New York City - Fleischmanns
- Bus Memphis - Nashville
- Bus from Philadelphia to New Orleans
- Coach San Diego - Victorville
- Bus Las Vegas - Anaheim
- Bus from Houston to Brownsville
- Coach Los Angeles - Chico
- Bus Albany - Ridgewood
- Bus from Albany to New York City
- Coach New Orleans - Atlanta
- Bus New York City - Philadelphia
- Bus from Rancho Cucamonga to Los Angeles
- Coach Boynton Beach - Boston
- Bus Boston - Rockford