Find coaches from St. Louis to Harrisburg

Next bus departures

Next departures from St. Louis to Harrisburg on 12 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.Bus
Gateway Station
Harrisburg Bus StationCheapestFastest

Last refresh of the prices: Yesterday at 9:28 PM CST.

Compare 2 ways to travel from St. Louis to Harrisburg

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Harrisburg. The journey takes about 19 hours 45 minutes and with fares starting at just R 1 461, it presents an excellent value for a comfortable ride.

3bus per day
19h 45mAverage duration
1158 kmDistance
29kgCO₂ emissions
Bus
Average priceR 1 461 - R 3 199Average duration19h 45m
29kg CO₂e
Train
Average priceR 3 184 - R 13 597Average duration1d 3h
105kg CO₂e

Frequently asked questions about travelling from St. Louis to Harrisburg by bus

  1. How much does a bus ticket from St. Louis to Harrisburg cost?

    The bus ticket price from St. Louis to Harrisburg starts at R 1 461. The best way to find cheap bus tickets from St. Louis to Harrisburg is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from St. Louis to Harrisburg?

    The average travel time between St. Louis and Harrisburg is around 19h 45m, although the fastest bus will take about 19h 20m. This is the time it takes to travel the 1158 km that separates the two cities.

  3. How many daily bus connections are there between St. Louis and Harrisburg?

    The number of buses from St. Louis to Harrisburg can differ depending on the day of the week. On average, there are 3 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from St. Louis to Harrisburg by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from St. Louis to Harrisburg?

    When taking the bus from St. Louis to Harrisburg, you can travel comfortably and safely with Greyhound, FlixBus.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/11
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11/11
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Today
R 2 037
13/11
No data
14/11
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15/11
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16/11
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17/11
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busbud logoThe cheapest trip from St. Louis to Harrisburg was searched and found on 12 Nov 2025 with a price of R 2 037

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Harrisburg as early as possible.

What's the cheapest way to go from St. Louis to Harrisburg?

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