Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | MLK Transportation Center | Des Moines | Cheapest | ||||
| Bus | MLK Transportation Center | Des Moines | Fastest | ||||
| Bus | MLK Transportation Center | Des Moines | No tags | ||||
| Bus | MLK Transportation Center | Des Moines | No tags |
Last refresh of the prices: Last Wednesday at 4:46 PM CST.
Get from Sioux City to Des Moines
The journey takes about 15 hours 35 minutes, and with fares starting at just R 2 821, it presents an excellent value for a comfortable ride.
Where are the popular stops in Sioux City and Des Moines?
Stops in Sioux City
- A
W Maple St
4110 W Maple St, Sioux Falls, SD 57107, USA
Stops in Des Moines
- A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314 - B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
Compare bus companies
Based on 766 reviews, the company was rated 3.9 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained about the Wi-Fi. Jefferson Lines ticket prices on this trip start at R 2 821
Frequently asked questions about travelling from Sioux City to Des Moines by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Sioux City to Des Moines?
The cheapest bus tickets from Sioux City to Des Moines start at R 2 821. The average price for this route is around R 2 821. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Sioux City to Des Moines?
The average bus journey time from Sioux City to Des Moines is 15h 35m, covering a distance of 252 km. The fastest bus gets you there in 14h 55m and is operated by Jefferson Lines.
Which bus companies service the Sioux City to Des Moines route?
Several major bus companies operate on this route with 2 buses available per day.
What is the earliest and latest departure time for the bus from Sioux City to Des Moines?
The earliest bus departs from Sioux City to Des Moines at 07:55. And the latest bus departs at 21:00.
What are the CO₂ emissions for the bus trip from Sioux City to Des Moines?
A bus trip from Sioux City to Des Moines produces an estimated 6 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Sioux City to Des Moines was searched and found on 01 Feb 2026 with a price of R 2 749To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Sioux City to Des Moines as early as possible.
You can expect to pay from R 2 749 to R 2 928 for a bus ticket from Sioux City to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 749, which is on 2026-02-04.
