Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal Sur | Santa Bárbara | Cheapest | ||||
| Bus | Terminal Sur | Santa Bárbara | Fastest | ||||
| Bus | Terminal Sur | Santa Bárbara | No tags | ||||
| Bus | Terminal Sur | Santa Bárbara | No tags | ||||
| Bus | Terminal Sur | Santa Bárbara | No tags |
Last refresh of the prices: Today at 1:52 AM -03.
Get from Santiago to Santa Bárbara
The journey takes about 5 hours 53 minutes, and with fares starting at just R 275, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santiago and Santa Bárbara?
Stops in Santiago
- ASantiago - Av Libertador Bernardo O'Higgins 3850, Santiago, Estación Central, Región Metropolitana, Chile
- B
San Borja
San Francisco de Borja 199-225, Santiago, Estación Central, Región Metropolitana, Chile - CTucapel Jiménez 21, 8340528 Santiago, Región Metropolitana, Chile
- DPdte. Riesco 6391-6399, Las Condes, Región Metropolitana, Chile
- EAv. Gral. Oscar Bonilla 418, Lo Prado, Región Metropolitana, Chile
- F
Zapadores
Los Zapadores 608, Recoleta, Región Metropolitana, Chile
Stops in Santa Bárbara
- A
Terminal Buses Aranguiz de Santa Bárbara
Baquedano 999, Santa Bárbara, Región del Bío Bío, Chile
Compare bus companies
Based on 157 reviews, the company was rated 3.8 stars on Busbud. Travellers were especially satisfied with the cleanliness and the ticket access but often complained with the Wi-Fi. Eme Bus ticket prices on this trip start at R 275
Frequently asked questions about travelling from Santiago, CL to Santa Bárbara, CL by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Santiago to Santa Bárbara?
The cheapest bus tickets from Santiago to Santa Bárbara start at R 275. The average price for this route is around R 341. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Santiago to Santa Bárbara?
The average bus journey time from Santiago to Santa Bárbara is 5h 53m, covering a distance of 484 km. The fastest bus gets you there in 5h 53m and is operated by Eme Bus.
Which bus companies service the Santiago to Santa Bárbara route?
Several major bus companies operate on this route with 2 buses available per day.
What is the earliest and latest departure time for the bus from Santiago to Santa Bárbara?
The earliest bus departs from Santiago to Santa Bárbara at 08:45. And the latest bus departs at 22:30.
What are the CO₂ emissions for the bus trip from Santiago to Santa Bárbara?
A bus trip from Santiago to Santa Bárbara produces an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santiago, CL to Santa Bárbara, CL was searched and found on 29 Jan 2026 with a price of R 301To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago, CL to Santa Bárbara, CL as early as possible.
You can expect to pay from R 301 to R 543 for a bus ticket from Santiago, CL to Santa Bárbara, CL based on the last 2 days. You can expect to find the cheapest price for the trip at R 301, which is on 2026-01-29.
