Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | SANTANDER | LYON | Cheapest | ||||
 | Bus | Santander (Estacion de Autobuses) | Lyon | Fastest | ||||
| Bus | SANTANDER | LYON | No tags | ||||
| Bus | Santander (Estacion de Autobuses) | Perrache | No tags | ||||
| Bus | Santander (Estacion de Autobuses) | Aéroport LYS | No tags |
Last refresh of the prices: Today at 3:30 PM CET.
Compare 2 ways to travel from Santander to Lyon
Among the sustainable travel choices, the carpool stands out as a good way to reach Lyon. The journey takes about 10 hours 50 minutes and with fares starting at just R 1 444, it presents an excellent value for a comfortable ride.
| Average price | Average duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average priceR 1 258 - R 3 237 | Average duration19h 55m | 18kg CO₂e | ||
Carpool | Average priceR 1 444 - R 1 444 | Average duration10h 50m | 31kg CO₂e |
Where are the popular stops in Santander and Lyon?
Stops in Santander
- ACalle Navas de Tolosa, 2, 39002 Santander, Cantabria, Spain
- B
Santander Airport
- C
Av. de los Castros 43A
Av. de los Castros 43A, 39005 Santander, Cantabria, Spain - D
Calle Camarreal-Ojaiz
Calle Camarreal-Ojaiz, 52, 39011 Santander, Cantabria, Spain - E
Av. de Pontejos
Av. de Pontejos, 33A, 39005 Santander, Cantabria, Spain - F
Estación Marítima
39002 Santander, Cantabria, Spain
Stops in Lyon
- ARue de Esplanade, 69002 Lyon, France
- B
Lyon Airport
- C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - FLes Charrières, 69570 Dardilly, France
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Frequently asked questions about travelling from Santander to Lyon by bus
How much does a bus ticket from Santander to Lyon cost?
The bus ticket price from Santander to Lyon starts at R 1 258. The best way to find cheap bus tickets from Santander to Lyon is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Santander to Lyon?
The average travel time between Santander and Lyon is around 19h 55m, although the fastest bus will take about 15h 40m. This is the time it takes to travel the 732 km that separates the two cities.
How many daily bus connections are there between Santander and Lyon?
The number of buses from Santander to Lyon can differ depending on the day of the week. On average, there are 1 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Santander to Lyon by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Santander to Lyon?
When taking the bus from Santander to Lyon, you can travel comfortably and safely with FlixBus, ALSA, BlaBlaCar Bus.
What are the departure and arrival stations when taking the bus from Santander to Lyon?
Buses travelling between Santander and Lyon leave from Calle Navas de Tolosa, 2 or Santander Airport and arrive at Perrache, Lyon Airport, Lyon.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santander to Lyon was searched and found on 28 Nov 2025 with a price of R 584To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santander to Lyon as early as possible.
You can expect to pay from R 584 to R 2 388 for a bus ticket from Santander to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at R 584, which is on 2025-11-28.
