Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | San Francisco Bus Station | Santa Ana Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | 409 Townsend St, SF | Santa Ana Bus Station | No tags | ||||
| Bus | San Francisco Bus Station | Santa Ana Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | 409 Townsend St, SF | Santa Ana Bus Station | No tags | ||||
| Bus | San Francisco Bus Station | Santa Ana Bus Station | No tags |
Get from San Francisco to Santa Ana
The journey takes about 13 hours 40 minutes, and with fares starting at just R 1 178, it presents an excellent value for a comfortable ride.
Where are the popular stops in San Francisco and Santa Ana?
Stops in San Francisco
- A
Hyde/Beach (Fisherman's Wharf)
700 Beach Street, San Francisco, CA 94109, USA - B
Powell Station
25 Cyril Magnin St , San Francisco, CA 94102-2812 - C
Union Square Hilton
255 Mason St,, San Francisco, CA 94102-2114 - D
San Francisco Greyhound Station
200 Folsom St, San Francisco, CA 94105 - E
444 Townsend St.
444 Townsend St, San Francisco, CA 94107, USA
Stops in Santa Ana
- A
Santa Ana Greyhound Bus Station
1000 E Santa Ana Blvd, Santa Ana, CA 92701 - B
602 S Main St
602 S Main St, Santa Ana, CA 92701, USA
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Frequently asked questions about travelling from San Francisco, US to Santa Ana, US by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from San Francisco to Santa Ana?
The cheapest bus tickets from San Francisco to Santa Ana start at R 1 178. The average price for this route is around R 2 108. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from San Francisco to Santa Ana?
The average bus journey time from San Francisco to Santa Ana is 13h 40m, covering a distance of 616 km. The fastest bus gets you there in 10h 55m and is operated by Greyhound.
Which bus companies service the San Francisco to Santa Ana route?
What is the earliest and latest departure time for the bus from San Francisco to Santa Ana?
The earliest bus departs from San Francisco to Santa Ana at 06:30. And the latest bus departs at 22:40.
What are the CO₂ emissions for the bus trip from San Francisco to Santa Ana?
A bus trip from San Francisco to Santa Ana produces an estimated 15 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from San Francisco to Santa Ana?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from San Francisco to Santa Ana?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from San Francisco to Santa Ana?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from San Francisco to Santa Ana?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Francisco, US to Santa Ana, US was searched and found on 29 Nov 2025 with a price of R 956To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Francisco, US to Santa Ana, US as early as possible.
