Find coaches from San Francisco, US to San Diego, CA, US

Next departures

Next departures from San Francisco to San Diego on 14 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Amtrak
Mission St & Fremont St
Santa Fe DepotCheapest
Amtrak
Mission St & Fremont St
Santa Fe DepotFastest
Greyhound Lines, Inc. + FlixBus
San Francisco Bus Station
San Diego (Old Town-FlixBus)No tags
Greyhound Lines, Inc.
San Francisco Bus Station
Greyhound Bus StopNo tags
Amtrak
Mission St & Fremont St
Santa Fe DepotNo tags
Greyhound Lines, Inc. + FlixBus
San Francisco Bus Station
UCSD Health La Jolla StationNo tags
Greyhound Lines, Inc.
San Francisco Bus Station
Greyhound Bus StopNo tags
Amtrak
Mission St & Fremont St
Santa Fe DepotNo tags

Last refresh of the prices: Today at 4:17 AM PST.

Get from San Francisco to San Diego

This route is served by bus only

The journey takes about 14 hours 45 minutes, and with fares starting at just R 996, it presents an excellent value for a comfortable ride.

15bus per day
14h 45mAverage duration
719 kmDistance
18kgCO₂ emissions

Frequently asked questions about travelling from San Francisco, US to San Diego, CA, US by bus

  1. How much does a bus ticket from San Francisco to San Diego cost?

    The bus ticket price from San Francisco to San Diego starts at R 996. The best way to find cheap bus tickets from San Francisco to San Diego is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from San Francisco to San Diego?

    The average travel time between San Francisco and San Diego is around 14h 45m, although the fastest bus will take about 11h 40m. This is the time it takes to travel the 739 km that separates the two cities.

  3. How many daily bus connections are there between San Francisco and San Diego?

    The number of buses from San Francisco to San Diego can differ depending on the day of the week. On average, there are 15 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from San Francisco to San Diego by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from San Francisco to San Diego?

    When taking the bus from San Francisco to San Diego, you can travel comfortably and safely with Amtrak, FlixBus, Greyhound.

  5. What are the departure and arrival stations when taking the bus from San Francisco to San Diego?

    Buses travelling between San Francisco and San Diego leave from Hyde/Beach (Fisherman's Wharf) or Powell Station and arrive at Mission Valley Sheraton, Old Town Courtyard Marriot, Downtown Holiday Inn.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/11
R 1 133
12/11
R 1 133
Today
R 1 133
14/11
R 1 133
15/11
R 1 133
16/11
R 1 133
17/11
R 1 080
18/11
R 1 028
busbud logoThe cheapest trip from San Francisco, US to San Diego, CA, US was searched and found on 18 Nov 2025 with a price of R 1 028

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Francisco, US to San Diego, CA, US as early as possible.

You can expect to pay from R 1 028 to R 3 624 for a bus ticket from San Francisco, US to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 028, which is on 2025-11-18.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

People from around the world trust Busbud

Popular Buses Connecting San Francisco

Buses Leaving from San Francisco

Buses Going to San Francisco

Popular Buses Connecting San Diego

Buses Leaving from San Diego

Buses Going to San Diego