Find coaches from San Diego, CA, US to Santa Clara, US

Next departures

Next departures from San Diego to Santa Clara on 3 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Amtrak
    		Santa Fe Depot
    		Great America StationCheapest
    Amtrak
      		Santa Fe Depot
      		Santa Clara Transit CenterFastest

      Last refresh of the prices: Last Tuesday at 2:27 AM PDT.

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      Compare 2 ways to travel from San Diego to Santa Clara

      We recommend taking the train

      Among the sustainable travel choices, the train stands out as a good way to reach Santa Clara. The journey takes about 1 hour 54 minutes and with fares starting at just US$32, it presents an excellent value for a comfortable ride.

      22train per day
      1h 54mAverage duration
      132 kmDistance
      12kgCO₂ emissions
      Bus
      		Average priceUS$14 - US$14Average duration2h 5m
      3kg CO₂e
      Train
      		Average priceUS$32 - US$32Average duration1h 54m
      12kg CO₂e

      Bus San Diego, CA, US to Santa Clara, US: Trip Overview

      Average ticket priceUS$14
      Average bus trip duration2h 5m
      Number of daily buses1
      Earliest bus departure21:25
      Distance132 km

      San Diego to Santa Clara Bus

      With Busbud, comparing and booking tickets for a bus from San Diego to Santa Clara is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

      Bus service from San Diego to Santa Clara will be provided by the most trusted bus companies.

      Discover how much the bus trip from San Diego to Santa Clara will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

      Frequently asked questions on the trip San Diego, CA, US - Santa Clara, US

      1. How much does a bus ticket from San Diego to Santa Clara cost?

        The bus ticket price from San Diego to Santa Clara starts at US$14. The best way to find cheap bus tickets from San Diego to Santa Clara is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

      2. How long is the bus ride from San Diego to Santa Clara?

        The average travel time between San Diego and Santa Clara is around 2h 5m, although the fastest bus will take about 2h 5m. This is the time it takes to travel the 677 km that separates the two cities.

      3. How many daily bus connections are there between San Diego and Santa Clara?

        The number of buses from San Diego to Santa Clara can differ depending on the day of the week. On average, there are 1 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from San Diego to Santa Clara by comparing and selecting the bus that fits your travel style and budget on Busbud.

      4. Which bus companies travel from San Diego to Santa Clara?

        When taking the bus from San Diego to Santa Clara, you can travel comfortably and safely with Amtrak.

      Find cheapest prices for buses

      Price is for a one-way ticket for one passenger and based on past searches.

      Best price found
      31/10
      US$108
      01/11
      US$108
      Today
      US$108
      03/11
      US$108
      04/11
      US$108
      05/11
      US$108
      06/11
      US$108
      07/11
      US$108
      busbud logoThe cheapest trip from San Diego, CA, US to Santa Clara, US was searched and found on 31 Oct 2025 with a price of US$108

      To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to Santa Clara, US as early as possible.

      You can expect to pay from US$108 to US$109 for a bus ticket from San Diego, CA, US to Santa Clara, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$108, which is on 2025-11-03.

      About Bus Travel

      Bus Travel Tips

      Meet and talk to locals at the bus stations while travelling from San Diego to Santa Clara.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

      Much more than a mere vehicle taking you from San Diego to Santa Clara, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

      Buses have the smallest carbon footprint of all motorized transport modes. A bus going from San Diego to Santa Clara will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

      Make a music playlist for your bus ride from San Diego to Santa Clara, and enjoy the scenery to tunes from your own personal soundtrack.

      Did you know?

      One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

      The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

      It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

      What's the cheapest way to go from San Diego, CA, US to Santa Clara, US?

      busbud logoThe bus is the cheapest travel choice for this destination

      Will you be returning to San Diego, CA, US by bus?

      Bus from Santa Clara, US to San Diego, CA, US

      You can also go to Santa Clara, US by train

      Train from San Diego, CA, US to Santa Clara, US

      Why choose Busbud?

      The Best Way To Book Bus and Train Tickets

      Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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