How much is the bus ticket from Rome to Syracuse?

The cheapest bus tickets from Rome to Syracuse start at R 1 060. The average price for this route is around R 1 928. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

How long is the bus journey from Rome to Syracuse?

The average bus journey time from Rome to Syracuse is 21h 10m, covering a distance of 588 km. The fastest bus gets you there in 13h 10m and is operated by FlixBus .

Which bus companies service the Rome to Syracuse route?

Several major bus companies operate on this route with 3 buses available per day.

What is the earliest and latest departure time for the bus from Rome to Syracuse?

The earliest bus departs from Rome to Syracuse at 01:15. And the latest bus departs at 23:55.

What are the CO₂ emissions for the bus trip from Rome to Syracuse?

A bus trip from Rome to Syracuse produces an estimated 15 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

Bus Rome to Syracuse from R 559 | Refundable Tickets

Next bus departures

Next departures from Rome to Syracuse on 26 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	20:10	Rome Tiburtina Bus Station	13h 25m	09:35	Terminal Interbus	CheapestFastest
	Bus	22:35	Rome Fiumicino Airport	22h 5m	20:40	Terminal Interbus	No tags

Next departures from Rome to Syracuse on 29 December
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	20:10	Rome Tiburtina Bus Station	13h 25m	09:35	Terminal Interbus	CheapestFastest
Bus	22:35	Rome Fiumicino Airport	22h 5m	20:40	Terminal Interbus	No tags
Bus	02:45	Rome Tiburtina Bus Station	17h 55m	20:40	Terminal Interbus	No tags
Bus	22:40	Aeroporto Ciampino Airport (CIA)	22h	20:40	Terminal Interbus	No tags

Last refresh of the prices: Last Monday at 8:26 PM CET.

Compare 3 ways to travel from Rome to Syracuse

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as a good way to reach Syracuse. The journey takes about 9 hours 50 minutes and with fares starting at just R 1 181, it presents an excellent value for a comfortable ride.

1carpool per day

9h 50mAverage duration

588 kmDistance

25kgCO₂ emissions

	Average price	Average duration	CO₂ emissions
Bus	Average priceR 1 060 - R 2 922	Average duration21h 10m	CO₂ emissions 15kg CO₂e
Train	Average priceR 1 536 - R 4 612	Average duration12h 17m	CO₂ emissions 14kg CO₂e
Carpool	Average priceR 1 181 - R 1 420	Average duration9h 50m	CO₂ emissions 25kg CO₂e

Where are the popular stops in Rome and Syracuse?

Stops in Rome

A
Rome Ciampino Airport
Visit page
B
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy
Visit page
C
Rome Fiumicino Airport
Visit page
D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy
E
Roma
F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy

Stops in Syracuse

A
Fermata dell'autobus Siracusa
Viale Paolo Orsi, 20, 96100 Siracusa SR, Italy
Visit page
B
Siracusa
Piazzale della Stazione Centrale, 21, 96100 Siracusa SR, Italy
C
Siracusa - Terminal Bus (Stazione FS)
Viale Teocrito, 68-74, 96100 Siracusa SR, Italy

Compare bus companies

FlixBus

3.5/511 746 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

WiFi2.7

Based on 11746 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at R 1 060

IT Bus Companies: FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Rede Expressos, Trenitalia

Frequently asked questions about travelling from Rome to Syracuse by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

How much is the bus ticket from Rome to Syracuse?
The cheapest bus tickets from Rome to Syracuse start at R 1 060. The average price for this route is around R 1 928. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Rome to Syracuse?
The average bus journey time from Rome to Syracuse is 21h 10m, covering a distance of 588 km. The fastest bus gets you there in 13h 10m and is operated by FlixBus.
Which bus companies service the Rome to Syracuse route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Rome to Syracuse?
The earliest bus departs from Rome to Syracuse at 01:15. And the latest bus departs at 23:55.
What are the CO₂ emissions for the bus trip from Rome to Syracuse?
A bus trip from Rome to Syracuse produces an estimated 15 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

24/12

No data

25/12

No data

Today

R 1 855

27/12

R 1 499

28/12

No data

29/12

R 1 515

30/12

R 943

31/12

R 1 339

The cheapest trip from Rome to Syracuse was searched and found on 30 Dec 2025 with a price of R 943

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Syracuse as early as possible.

You can expect to pay from R 943 to R 3 105 for a bus ticket from Rome to Syracuse based on the last 2 days. You can expect to find the cheapest price for the trip at R 943, which is on 2025-12-30.