How much is the bus ticket from Rome to Syracuse?

The cheapest coach tickets from Rome to Syracuse start from £37. The average price for this route is around £61. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus journey from Rome to Syracuse?

The average bus journey time from Rome to Syracuse is 20h 55m, covering a distance of 365 miles. The fastest bus can take you there in 13h 25m and is operated by FlixBus .

Which bus companies service the Rome to Syracuse route?

Several major bus companies operate on this route with 3 buses available per day.

What is the earliest and latest departure time for the bus from Rome to Syracuse?

The earliest bus departs from Rome to Syracuse at 01:15. And the latest bus departs at 23:55.

What are the CO₂ emissions for the bus trip from Rome to Syracuse?

A bus journey from Rome to Syracuse produces an estimated 15 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

Bus Rome to Syracuse from £35 | Refundable Tickets

Next bus departures

Next departures from Rome to Syracuse on 27 November
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	22:40	Aeroporto Ciampino Airport (CIA)	22h	20:40	Terminal Interbus	Cheapest
Bus	20:10	Rome Tiburtina Bus Station	13h 25m	09:35	Terminal Interbus	Fastest
Bus	22:35	Rome Fiumicino Airport	22h 5m	20:40	Terminal Interbus	No tags

Last refresh of the prices: Yesterday at 16:46 CET.

Compare 3 ways to travel from Rome to Syracuse

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as a good way to reach Syracuse. The journey takes about 9 hours 30 minutes and with fares starting at just £34, it presents an excellent value for a comfortable ride.

2carpool per day

9h 30mAverage duration

365 milesDistance

25kgCO₂ emissions

	Average price	Average duration	CO₂ emissions
Bus	Average price£37 - £132	Average duration20h 55m	CO₂ emissions 15kg CO₂e
Train	Average price£45 - £206	Average duration12h 17m	CO₂ emissions 14kg CO₂e
Carpool	Average price£34 - £68	Average duration9h 30m	CO₂ emissions 25kg CO₂e

Where are the popular stops in Rome and Syracuse?

Stops in Rome

A
Rome Ciampino Airport
Visit page
B
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy
Visit page
C
Rome Fiumicino Airport
Visit page
D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy
E
Roma
F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy

Stops in Syracuse

A
Fermata dell'autobus Siracusa
Viale Paolo Orsi, 20, 96100 Siracusa SR, Italy
Visit page
B
Siracusa
Piazzale della Stazione Centrale, 21, 96100 Siracusa SR, Italy
C
Siracusa - Terminal Bus (Stazione FS)
Viale Teocrito, 68-74, 96100 Siracusa SR, Italy

Compare bus companies

FlixBus

3.5/511,455 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

WiFi2.7

Based on 11455 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at £37

IT Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Rede Expressos, Trenitalia

Frequently asked questions about travelling by bus from Rome to Syracuse

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

How much is the bus ticket from Rome to Syracuse?
The cheapest coach tickets from Rome to Syracuse start from £37. The average price for this route is around £61. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Rome to Syracuse?
The average bus journey time from Rome to Syracuse is 20h 55m, covering a distance of 365 miles. The fastest bus can take you there in 13h 25m and is operated by FlixBus.
Which bus companies service the Rome to Syracuse route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Rome to Syracuse?
The earliest bus departs from Rome to Syracuse at 01:15. And the latest bus departs at 23:55.
What are the CO₂ emissions for the bus trip from Rome to Syracuse?
A bus journey from Rome to Syracuse produces an estimated 15 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

25/11

£34

26/11

£81

Today

£71

28/11

£47

29/11

£41

30/11

£51

01/12

£40

02/12

£41

The cheapest trip from Rome to Syracuse was searched and found on 25 Nov 2025 with a price of £34

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Syracuse as early as possible.

You can expect to pay from £34 to £137 for a bus ticket from Rome to Syracuse based on the last 2 days. You can expect to find the cheapest price for the trip at £40, which is on 2025-12-01.