Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Port St Lucie (Park & Ride) | Jacksonville Bus Station | No tags | ||||
 | Bus | Port St Lucie (Park & Ride) | Jacksonville Bus Station | No tags | ||||
| Bus | Port St Lucie (Park & Ride) | Jacksonville Bus Station | No tags | ||||
| Bus | Port St Lucie (Park & Ride) | Jacksonville Bus Station | No tags | ||||
| Bus | Port St Lucie (Park & Ride) | Jacksonville Bus Station | No tags |
Get from Port Saint Lucie to Jacksonville
The journey takes about 6 hours 5 minutes, and with fares starting at just R 695, it presents an excellent value for a comfortable ride.
Where are the popular stops in Port Saint Lucie and Jacksonville?
Stops in Port Saint Lucie
- A
Port St Lucie Mobil Gas Bus Stop
1820 Sw Fountainview Blvd, Port Saint Lucie, FL 34986 - B
Port Saint Lucie - Wendys
1790 SW St Lucie W Blvd, Port St Lucie, FL 34986 - C
Port Saint LucieService Plaza
Florida's Turnpike, Milepost 144, Port St Lucie, FL 34984, USA - D
Port Saint Lucie Bus Stop
2198 SW Gatlin Blvd. Port St. Lucie, FL 34953
Stops in Jacksonville
- A3570 Clifford Ln, Jacksonville, FL 32209, USA
- B
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA - C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207 - D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA
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Frequently asked questions about travelling from Port Saint Lucie to Jacksonville, FL by bus
How much does a bus ticket from Port Saint Lucie to Jacksonville cost?
The bus ticket price from Port Saint Lucie to Jacksonville starts at R 695. The best way to find cheap bus tickets from Port Saint Lucie to Jacksonville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Port Saint Lucie to Jacksonville?
The average travel time between Port Saint Lucie and Jacksonville is around 6h 5m, although the fastest bus will take about 6h 5m. This is the time it takes to travel the 362 km that separates the two cities.
How many daily bus connections are there between Port Saint Lucie and Jacksonville?
The number of buses from Port Saint Lucie to Jacksonville can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Port Saint Lucie to Jacksonville by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Port Saint Lucie to Jacksonville?
When taking the bus from Port Saint Lucie to Jacksonville, you can travel comfortably and safely with FlixBus, Greyhound.
What are the departure and arrival stations when taking the bus from Port Saint Lucie to Jacksonville?
Buses travelling between Port Saint Lucie and Jacksonville leave from Port St Lucie Mobil Gas Bus Stop or Port Saint Lucie - Wendys and arrive at Jacksonville Amtrak Station, W Forsyth St, Kings Avenue Station.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Port Saint Lucie to Jacksonville, FL was searched and found on 19 Nov 2025 with a price of R 728To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Port Saint Lucie to Jacksonville, FL as early as possible.
You can expect to pay from R 728 to R 1 580 for a bus ticket from Port Saint Lucie to Jacksonville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at R 808, which is on 2025-11-22.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
