Find coaches from Philadelphia, PA to St. Louis

Next departures

Next departures from Philadelphia to St. Louis on 4 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
    		Frazer - 56-40 Matthews Rd
    		Gateway StationCheapest
    Greyhound Lines, Inc.
      		199 Spring Garden St.
      		Gateway StationFastest
      Greyhound Lines, Inc.
        		199 Spring Garden St.
        		Gateway StationNo tags
        FlixBus + Greyhound Lines, Inc.
          		Philadelphia, 199 Spring Garden St
          		Gateway StationNo tags
          Greyhound Lines, Inc.
            		199 Spring Garden St.
            		Gateway StationNo tags

            Last refresh of the prices: Last Friday at 5:37 PM EDT.

            Accepted payments

            • Visa
            • MasterCard
            • American Express
            • China Union Pay
            • Diners Club Canada
            • Discover Click to Pay
            • JCB payment
            • Klarna (Pay over time)
            • Google Pay

            Compare 2 ways to travel from Philadelphia to St. Louis

            We recommend taking the bus

            Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 1 day, 3 hours 40 minutes and with fares starting at just US$69, it presents an excellent value for a comfortable ride.

            19bus per day
            1d 3hAverage duration
            1304 kmDistance
            33kgCO₂ emissions
            Bus
            		Average priceUS$69 - US$334Average duration1d 3h
            33kg CO₂e
            Train
            		Average priceUS$139 - US$2 678Average duration1d 8h
            118kg CO₂e

            Bus Philadelphia, PA to St. Louis: Trip Overview

            Average ticket priceUS$144
            Average bus trip duration1d 3h
            Number of daily buses19
            Earliest bus departure01:50
            Distance1303 km
            Latest bus departure23:15

            Philadelphia to St. Louis Bus

            Busbud helps you find a bus from Philadelphia to St. Louis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

            Bus service from Philadelphia to St. Louis will be provided by the most trusted bus companies.

            Whether it is cheap bus tickets or more luxurious buses going to St. Louis from Philadelphia, we help you find what you're looking for based on how much of a budget you have.

            Frequently asked questions on the trip Philadelphia, PA - St. Louis

            1. How much does a bus ticket from Philadelphia to St. Louis cost?

              The bus ticket price from Philadelphia to St. Louis starts at US$69. The best way to find cheap bus tickets from Philadelphia to St. Louis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

            2. How long is the bus ride from Philadelphia to St. Louis?

              The average travel time between Philadelphia and St. Louis is around 1d 3h, although the fastest bus will take about 19h 45m. This is the time it takes to travel the 1303 km that separates the two cities.

            3. How many daily bus connections are there between Philadelphia and St. Louis?

              The number of buses from Philadelphia to St. Louis can differ depending on the day of the week. On average, there are 19 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Philadelphia to St. Louis by comparing and selecting the bus that fits your travel style and budget on Busbud.

            4. Which bus companies travel from Philadelphia to St. Louis?

              When taking the bus from Philadelphia to St. Louis, you can travel comfortably and safely with Greyhound, FlixBus.

            5. What are the departure and arrival stations when taking the bus from Philadelphia to St. Louis?

              Buses travelling between Philadelphia and St. Louis leave from Philadelphia Airport or Independence Travel Center and arrive at Gateway Station.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            01/11
            US$124
            02/11
            US$113
            Today
            US$92
            04/11
            US$83
            05/11
            US$74
            06/11
            US$94
            07/11
            US$94
            08/11
            No data
            busbud logoThe cheapest trip from Philadelphia, PA to St. Louis was searched and found on 05 Nov 2025 with a price of US$74

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to St. Louis as early as possible.

            You can expect to pay from US$74 to US$281 for a bus ticket from Philadelphia, PA to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$74, which is on 2025-11-05.

            About Bus Travel

            Bus Travel Tips

            Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Philadelphia and St. Louis!

            Much more than a mere vehicle taking you from Philadelphia to St. Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

            Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Philadelphia to St. Louis.

            Tune out to the fine sounds of your best music playlist on your bus trip from Philadelphia to St. Louis while indulging in miles on end of beautiful scenic views.

            Did you know?

            Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

            The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

            Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

            What's the cheapest way to go from Philadelphia, PA to St. Louis?

            busbud logoThe bus is the cheapest travel choice for this destination

            Will you be returning to Philadelphia, PA by bus?

            Bus from St. Louis to Philadelphia, PA

            You can also go to St. Louis by train

            Train from Philadelphia, PA to St. Louis

            Why choose Busbud?

            The Best Way To Book Bus and Train Tickets

            Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

            People from around the world trust Busbud

            ‌

            Popular Buses Connecting Philadelphia

            Buses Leaving from Philadelphia

            Buses Going to Philadelphia

            Popular Buses Connecting St. Louis

            Buses Leaving from St. Louis

            Buses Going to St. Louis