Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | 199 Spring Garden St. | Gateway Station | Cheapest | ||||
| Bus | 199 Spring Garden St. | Gateway Station | Fastest | ||||
| Bus | 199 Spring Garden St. | Gateway Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Philadelphia, 199 Spring Garden St | Gateway Station | No tags | ||||
| Bus | 199 Spring Garden St. | Gateway Station | No tags |
Last refresh of the prices: Yesterday at 22:55 EST.
Compare 2 ways to travel from Philadelphia to St. Louis
Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 1 day, 3 hours 55 minutes and with fares starting at just £54, it presents an excellent value for a comfortable ride.
Where are the popular stops in Philadelphia and St. Louis?
Stops in Philadelphia
- BOff of Race Street between 5th Street and, N 6th St, Philadelphia, PA 19106, USA
- C
#2842 St.Vincent St
15th St Trolley Station, Philadelphia, PA 19102, USA - D
Bus Station
1001 Filbert St, Philadelphia, PA 19107, USA - E
Island Av & Suffolk Av MBFS
3000 Island Ave, Philadelphia, PA 19153, USA - F
NRG SEPTA Station
3701 Broad St, Philadelphia, PA 19148, USA
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Frequently asked questions about travelling by bus from Philadelphia, PA to St. Louis
What's the distance between Philadelphia and St. Louis by coach?
The distance between Philadelphia and St. Louis by coach is approximately 808 miles (1303 km).
How can I travel from Philadelphia to St. Louis avoiding air travel?
You have the option to select the coach for your journey on this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Philadelphia, PA to St. Louis was searched and found on 20 Nov 2025 with a price of £83To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to St. Louis as early as possible.
You can expect to pay from £83 to £233 for a bus ticket from Philadelphia, PA to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at £87, which is on 2025-11-23.
What's the cheapest way to go from Philadelphia, PA to St. Louis?
The bus is the cheapest travel choice for this destination
