Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Panama City Beach Station | BILOXI | Cheapest | ||||
 | Bus | Panama City Beach Station | BILOXI | Fastest |
Last refresh of the prices: Today at 10:43 AM CST.
Get from Panama City to Biloxi
The journey takes about 6 hours 5 minutes, and with fares starting at just R 1 500, it presents an excellent value for a comfortable ride.
Where are the popular stops in Panama City and Biloxi?
Stops in Panama City
- A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401
Stops in Biloxi
- A11332 Cedar Lake Rd, Biloxi, MS 39532, USA
- B
Transit Center
820 Dr Martin Luther King Jr Blvd, Biloxi, MS 39530, USA
Compare bus companies
Based on 87478 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 1 500
Frequently asked questions about travelling from Panama City, US to Biloxi by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Panama City to Biloxi?
The cheapest bus tickets from Panama City to Biloxi start at R 1 500. The average price for this route is around R 1 695. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Panama City to Biloxi?
The average bus journey time from Panama City to Biloxi is 6h 5m, covering a distance of 301 km. The fastest bus gets you there in 6h 5m and is operated by Greyhound.
Which bus companies service the Panama City to Biloxi route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Panama City to Biloxi?
The earliest bus departs from Panama City to Biloxi at 14:15. And the latest bus departs at 21:40.
What are the CO₂ emissions for the bus trip from Panama City to Biloxi?
A bus trip from Panama City to Biloxi produces an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Panama City, US to Biloxi was searched and found on 05 Jan 2026 with a price of R 1 759To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to Biloxi as early as possible.
You can expect to pay from R 1 759 to R 1 759 for a bus ticket from Panama City, US to Biloxi based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 759, which is on 2026-01-05.
