Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal del Norte | Central de autobuses de Valle de Santiago | Cheapest | ||||
| Bus | Terminal del Norte | Central de autobuses de Valle de Santiago | Fastest |
Last refresh of the prices: Yesterday at 11:12 PM CST.
Get from Mexico City to Valle de Santiago
The journey takes about 4 hours, and with fares starting at just R 826, it presents an excellent value for a comfortable ride.
Compare bus companies
Primera Plus offers 2 daily departures, and you can find tickets starting at R 826. The quickest ride takes around 245. Primera Plus offers a cost-effective solution to get you where you need to be.
Frequently asked questions about travelling from Mexico City to Valle de Santiago by bus
How much does a bus ticket from Mexico City to Valle de Santiago cost?
The bus ticket price from Mexico City to Valle de Santiago starts at R 826. The best way to find cheap bus tickets from Mexico City to Valle de Santiago is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Mexico City to Valle de Santiago?
The average travel time between Mexico City and Valle de Santiago is around 4h, although the fastest bus will take about 4h. This is the time it takes to travel the 241 km that separates the two cities.
How many daily bus connections are there between Mexico City and Valle de Santiago?
The number of buses from Mexico City to Valle de Santiago can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Mexico City to Valle de Santiago by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Mexico City to Valle de Santiago?
When taking the bus from Mexico City to Valle de Santiago, you can travel comfortably and safely with Primera Plus.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mexico City to Valle de Santiago was searched and found on 20 Nov 2025 with a price of R 868To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mexico City to Valle de Santiago as early as possible.
You can expect to pay from R 868 to R 869 for a bus ticket from Mexico City to Valle de Santiago based on the last 2 days. You can expect to find the cheapest price for the trip at R 868, which is on 2025-11-21.
