Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Terminal del Norte | Santa Fé de Antioquia | Cheapest | |||||
 | Terminal del Norte | Santa Fé de Antioquia | Fastest | |||||
| Terminal del Norte | Santa Fé de Antioquia | No tags | |||||
| Terminal del Norte | Santa Fé de Antioquia | No tags | |||||
| Terminal del Norte | Santa Fé de Antioquia | No tags |
Last refresh of the prices: Yesterday at 1:13 PM -05.
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Get from Medellin to Santa Fe de Antioquia
The journey takes about 1 hour 18 minutes, and with fares starting at just R 78, it presents an excellent value for a comfortable ride.
Bus Medellin to Santa Fe de Antioquia: Trip Overview
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Medellin to Santa Fe de Antioquia Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Medellin to Santa Fe de Antioquia.
We make it our job to connect you with the most dependable bus companies that cover bus service from Medellin to Santa Fe de Antioquia.
Discover how much the bus trip from Medellin to Santa Fe de Antioquia will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Frequently asked questions on the trip Medellin - Santa Fe de Antioquia
How much does a bus ticket from Medellin to Santa Fe de Antioquia cost?
The bus ticket price from Medellin to Santa Fe de Antioquia starts at R 78. The best way to find cheap bus tickets from Medellin to Santa Fe de Antioquia is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Medellin to Santa Fe de Antioquia?
The average travel time between Medellin and Santa Fe de Antioquia is around 1h 18m, although the fastest bus will take about 1h 18m. This is the time it takes to travel the 45 km that separates the two cities.
How many daily bus connections are there between Medellin and Santa Fe de Antioquia?
The number of buses from Medellin to Santa Fe de Antioquia can differ depending on the day of the week. On average, there are 8 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Medellin to Santa Fe de Antioquia by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Medellin to Santa Fe de Antioquia?
When taking the bus from Medellin to Santa Fe de Antioquia, you can travel comfortably and safely with Sotrauraba, Rapido Ochoa, Gomez Hernandez.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Medellin to Santa Fe de Antioquia was searched and found on 09 Nov 2025 with a price of R 71To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Medellin to Santa Fe de Antioquia as early as possible.
You can expect to pay from R 71 to R 81 for a bus ticket from Medellin to Santa Fe de Antioquia based on the last 2 days. You can expect to find the cheapest price for the trip at R 71, which is on 2025-11-09.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Medellin to Santa Fe de Antioquia but it'll also be endearing to native speakers who will surely appreciate your effort.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Medellin to Santa Fe de Antioquia.
Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Medellin to Santa Fe de Antioquia will emit half the CO2 emitted by a train, and radically less than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Medellin to Santa Fe de Antioquia.
Did you know?
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
Top travelled bus routes
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Popular Buses Connecting Medellin
Buses Leaving from Medellin
- Bus from Medellin to Bogotá
- Coach Medellin - Guatape
- Bus Medellin - Cartagena
- Bus from Medellin to Cali
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- Coach Medellin - Cañasgordas
- Bus Medellin - Saldaña
- Bus from Medellin to Mompós
- Coach Medellin - Tabacal
- Bus Medellin - Chinú
- Bus from Medellin to Aracataca
- Coach Medellin - Santa Fe de Antioquia
- Bus Medellin - Riohacha
Buses Going to Medellin
- Bus from Bogotá to Medellin
- Coach Cali - Medellin
- Bus Montería - Medellin
- Bus from Ibagué to Medellin
- Coach Manizales - Medellin
- Bus Pereira - Medellin
- Bus from Sahagún to Medellin
- Coach San Rafael - Medellin
- Bus Fundacion - Medellin
- Bus from San Juan Nepomuceno to Medellin
- Coach Natagaima - Medellin
- Bus Sampués - Medellin
- Bus from Caucasia to Medellin
- Coach Cereté - Medellin
- Bus Tuluá - Medellin