Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Madrid (South) | Südseite Hauptbahnhof | Cheapest | |||||
| Madrid (South) | Südseite Hauptbahnhof | Fastest | |||||
| Madrid (South) | Südseite Hauptbahnhof | No tags | |||||
Flixbus + Flixtrain | Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4 | Karlsruhe Hbf | No tags | |||||
| Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4 | Südseite Hauptbahnhof | No tags |
Last refresh of the prices: Today at 9:03 AM CET.
Get from Madrid to Karlsruhe
The journey takes about 1 day, 2 hours 15 minutes, and with fares starting at just R 1 332, it presents an excellent value for a comfortable ride.
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Where are the popular stops in Madrid and Karlsruhe?
Frequently asked questions about travelling from Madrid to Karlsruhe by bus
How much does a bus ticket from Madrid to Karlsruhe cost?
The bus ticket price from Madrid to Karlsruhe starts at R 1 332. The best way to find cheap bus tickets from Madrid to Karlsruhe is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Madrid to Karlsruhe?
The average travel time between Madrid and Karlsruhe is around 1d 2h, although the fastest bus will take about 1d 2h. This is the time it takes to travel the 1350 km that separates the two cities.
How many daily bus connections are there between Madrid and Karlsruhe?
The number of buses from Madrid to Karlsruhe can differ depending on the day of the week. On average, there are 1 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Madrid to Karlsruhe by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Madrid to Karlsruhe?
When taking the bus from Madrid to Karlsruhe, you can travel comfortably and safely with BlaBlaCar Bus, FlixBus.
What are the departure and arrival stations when taking the bus from Madrid to Karlsruhe?
Buses travelling between Madrid and Karlsruhe leave from Estación Sur or Madrid-Barajas Airport and arrive at Südseite Hauptbahnhof, Karlsruhe Hbf, Goethestraße.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Madrid to Karlsruhe was searched and found on 21 Nov 2025 with a price of R 1 272To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Madrid to Karlsruhe as early as possible.
You can expect to pay from R 1 272 to R 3 737 for a bus ticket from Madrid to Karlsruhe based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 272, which is on 2025-11-21.
