Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Luzern | PRG Airport | CheapestFastest | ||||
| Bus | Luzern | PRG Airport | No tags | ||||
| Bus | Luzern | PRG Airport | No tags |
Last refresh of the prices: Last Monday at 5:40 PM CET.
Get from Lucerne to Prague
The journey takes about 18 hours, and with fares starting at just R 874, it presents an excellent value for a comfortable ride.
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Where are the popular stops in Lucerne and Prague?
Stops in Lucerne
- AEuropaplatz, 6005 Luzern, Switzerland
- B
Lucerne Carparkplatz Inseliquai
Inseliquai, 6005 Luzern, Switzerland - C
Luzern Omnibusbahnhof
Luzern,, Switzerland
Stops in Prague
- AAviatická, 161 08, Praha 6, Czechia
- BKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- C
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - DChlumecká, 198 00 Praha 20, Czech Republic
- ETomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- F300/8 Wilsonova, 110 00 Praha, Czechia
Frequently asked questions about travelling from Lucerne to Prague by bus
How much does a bus ticket from Lucerne to Prague cost?
The bus ticket price from Lucerne to Prague starts at R 874. The best way to find cheap bus tickets from Lucerne to Prague is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Lucerne to Prague?
The average travel time between Lucerne and Prague is around 18h, although the fastest bus will take about 11h 8m. This is the time it takes to travel the 563 km that separates the two cities.
How many daily bus connections are there between Lucerne and Prague?
The number of buses from Lucerne to Prague can differ depending on the day of the week. On average, there are 12 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Lucerne to Prague by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Lucerne to Prague?
When taking the bus from Lucerne to Prague, you can travel comfortably and safely with FlixBus, RegioJet.
What are the departure and arrival stations when taking the bus from Lucerne to Prague?
Buses travelling between Lucerne and Prague leave from Parking Bus Inselipark or Lucerne Carparkplatz Inseliquai and arrive at PRG Airport, Florenc, Zličín.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Lucerne to Prague was searched and found on 24 Nov 2025 with a price of R 846To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lucerne to Prague as early as possible.
You can expect to pay from R 846 to R 1 886 for a bus ticket from Lucerne to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at R 846, which is on 2025-11-24.
