Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Knoxville Bus Station | WJW Investments Bus Stop | CheapestFastest |
Last refresh of the prices: Yesterday at 7:15 PM EST.
Get from Knoxville to Lexington
The journey takes about 3 hours 45 minutes, and with fares starting at just R 536, it presents an excellent value for a comfortable ride.
Where are the popular stops in Knoxville and Lexington?
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Stops in Lexington
- A477 W New Circle Rd, Lexington, KY 40511
- B1801 Alexandria Dr, Lexington, KY 40504, USA
Compare bus companies
Based on 87492 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 536
Greyhound Knoxville Lexington recent customer reviews
It was going well but then it broke down and we had to wait for another bus to come from 2 hours away
Laurel T.
Awesome. Great
Jifin V.
Frequently asked questions about travelling from Knoxville, TN to Lexington, KY by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Knoxville to Lexington?
The cheapest bus tickets from Knoxville to Lexington start at R 536. The average price for this route is around R 713. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Knoxville to Lexington?
The average bus journey time from Knoxville to Lexington is 3h 45m, covering a distance of 237 km. The fastest bus gets you there in 3h 45m and is operated by Greyhound.
Which bus companies service the Knoxville to Lexington route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Knoxville to Lexington?
The earliest bus departs from Knoxville to Lexington at 22:00. And the latest bus departs at 22:00.
What are the CO₂ emissions for the bus trip from Knoxville to Lexington?
A bus trip from Knoxville to Lexington produces an estimated 6 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Knoxville, TN to Lexington, KY was searched and found on 13 Jan 2026 with a price of R 414To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Lexington, KY as early as possible.
You can expect to pay from R 414 to R 575 for a bus ticket from Knoxville, TN to Lexington, KY based on the last 2 days. You can expect to find the cheapest price for the trip at R 414, which is on 2026-01-13.
