Find coaches from Itajaí to Santiago, BR

Next departures

Next departures from Itajaí to Santiago on 3 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
União Santa Cruz
    		Itajaí Bus Terminal
    		Estação Rodoviária De SantiagoCheapestFastest
    União Santa Cruz
      		Itajaí Bus Terminal
      		Estação Rodoviária De SantiagoNo tags

      Last refresh of the prices: Today at 12:56 AM -03.

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      Get from Itajaí to Santiago

      This route is served by bus only

      The journey takes about 16 hours 45 minutes, and with fares starting at just US$74, it presents an excellent value for a comfortable ride.

      1bus per day
      16h 45mAverage duration
      656 kmDistance
      16kgCO₂ emissions

      Bus Itajaí to Santiago, BR: Trip Overview

      Average ticket priceUS$74
      Average bus trip duration16h 45m
      Number of daily buses1
      Earliest bus departure20:00
      Distance656 km

      Itajaí to Santiago Bus

      Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Itajaí to Santiago.

      Bus service from Itajaí to Santiago will be provided by the most trusted bus companies.

      Whether it is cheap bus tickets or more luxurious buses going to Santiago from Itajaí, we help you find what you're looking for based on how much of a budget you have.

      Frequently asked questions on the trip Itajaí - Santiago, BR

      1. How much does a bus ticket from Itajaí to Santiago cost?

        The bus ticket price from Itajaí to Santiago starts at US$74. The best way to find cheap bus tickets from Itajaí to Santiago is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

      2. How long is the bus ride from Itajaí to Santiago?

        The average travel time between Itajaí and Santiago is around 16h 45m, although the fastest bus will take about 16h 45m. This is the time it takes to travel the 659 km that separates the two cities.

      3. How many daily bus connections are there between Itajaí and Santiago?

        The number of buses from Itajaí to Santiago can differ depending on the day of the week. On average, there are 1 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Itajaí to Santiago by comparing and selecting the bus that fits your travel style and budget on Busbud.

      4. Which bus companies travel from Itajaí to Santiago?

        When taking the bus from Itajaí to Santiago, you can travel comfortably and safely with União Santa Cruz.

      5. What are the departure and arrival stations when taking the bus from Itajaí to Santiago?

        Buses travelling between Itajaí and Santiago leave from Itajaí Bus Terminal or Terminal Rodoviário Internacional de Itajaí and arrive at Santiago Onibus.

      Find cheapest prices for buses

      Price is for a one-way ticket for one passenger and based on past searches.

      Best price found
      31/10
      No data
      01/11
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      Today
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      03/11
      US$62
      04/11
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      05/11
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      06/11
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      07/11
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      busbud logoThe cheapest trip from Itajaí to Santiago, BR was searched and found on 03 Nov 2025 with a price of US$62

      To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Itajaí to Santiago, BR as early as possible.

      You can expect to pay from US$62 to US$79 for a bus ticket from Itajaí to Santiago, BR based on the last 2 days. You can expect to find the cheapest price for the trip at US$62, which is on 2025-11-03.

      About Bus Travel

      Bus Travel Tips

      If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Itajaí to Santiago but it'll also be endearing to native speakers who will surely appreciate your effort.

      Much more than a mere vehicle taking you from Itajaí to Santiago, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

      Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Itajaí to Santiago.

      Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Itajaí to Santiago.

      Did you know?

      9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

      The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

      Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

      Will you be returning to Itajaí by bus?

      Bus from Santiago, BR to Itajaí

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