Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Itajaí Bus Terminal | Estação Rodoviária De Santiago | CheapestFastest |
Last refresh of the prices: Yesterday at 10:30 PM -03.
Get from Itajaí to Santiago
The journey takes about 16 hours 45 minutes, and with fares starting at just $106, it presents an excellent value for a comfortable ride.
Where are the popular stops in Itajaí and Santiago?
Stops in Itajaí
- AAv. Gov. Adolfo Konder, 1583-1705 - Cidade Nova, Itajaí - SC, Brazil
- B
Terminal Rodoviário Internacional de Itajaí
Avenida Governador Adolfo Konder, 1201 - São Vicente, Itajaí - SC 88308-000 - C
Vila Operaria - Itajai
Vila Operária, Rio de Janiero, Brasil
Stops in Santiago
- AR. Flôres da Cunha, 1755 - Centro, Santiago - RS, 97700-000, Brazil
Compare bus companies
Based on 16 reviews, the company was rated 4.5 stars on Busbud. Travellers were especially satisfied with the staff and the seats but often complained with the WiFi. União Santa Cruz ticket prices on this trip start at $106
Frequently asked questions about travelling from Itajaí to Santiago, BR by bus
How far is Itajaí from Santiago?
The distance between Itajaí and Santiago is around 659 km (409 miles).
What are the departure and arrival locations for buses traveling from Itajaí to Santiago?
Buses traveling this route start their trip at Itajaí Bus Terminal, in Itajaí, and end it at Santiago Onibus, in Santiago.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Itajaí to Santiago, BR was searched and found on Nov 24, 2025 with a price of $89To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Itajaí to Santiago, BR, as early as possible.
