How much does a bus ticket from Isernia to Rome cost?

The bus ticket price from Isernia to Rome starts at US$14. The best way to find cheap bus tickets from Isernia to Rome is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

How long is the bus ride from Isernia to Rome?

The average travel time between Isernia and Rome is around 9h 5m, although the fastest bus will take about 2h 10m. This is the time it takes to travel the 150 km that separates the two cities.

How many daily bus connections are there between Isernia and Rome?

The number of buses from Isernia to Rome can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Isernia to Rome by comparing and selecting the bus that fits your travel style and budget on Busbud.

Which bus companies travel from Isernia to Rome?

When taking the bus from Isernia to Rome, you can travel comfortably and safely with FlixBus, FlixBus.

Bus Isernia to Rome from US$17 | Refundable Tickets

Next departures

Next departures from Isernia to Rome on 2 November
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
15:50	Isernia	6h 55m	22:45	Rome Tiburtina Bus Station	CheapestFastest
11:25	Isernia	9h 50m	21:15	Rome Fiumicino Airport	No tags
15:50	Isernia	9h 10m	01:00	Rome Fiumicino Airport	No tags
11:25	Isernia	9h 5m	20:30	Rome Tiburtina Bus Station	No tags

Last refresh of the prices: Yesterday at 11:48 AM CET.

Compare 3 ways to travel from Isernia to Rome

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as a good way to reach Rome. The journey takes about 2 hours and with fares starting at just US$11, it presents an excellent value for a comfortable ride.

5carpool per day

2hAverage duration

149 kmDistance

6kgCO₂ emissions

	Average price	Average duration	CO₂ emissions
Bus	Average priceUS$14 - US$99	Average duration9h 5m	CO₂ emissions 4kg CO₂e
Train	Average priceUS$21 - US$22	Average duration5h	CO₂ emissions 4kg CO₂e
Carpool	Average priceUS$11 - US$24	Average duration2h	CO₂ emissions 6kg CO₂e

Bus Isernia to Rome: Trip Overview

Average ticket priceUS$38

Average bus trip duration9h 5m

Number of daily buses2

Earliest bus departure11:25

Distance146 km

Latest bus departure15:50

Compare bus companies

FlixBus

3.5/511 144 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

WiFi2.7

FlixBus

3.5/511 144 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

WiFi2.7

IT Bus Companies: FlixBus, BlaBlaCar Bus, Rede Expressos, Trenitalia, MarinoBus, Infobus, Itabus

Isernia to Rome Bus

Busbud helps you find a bus from Isernia to Rome. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Isernia to Rome from the most reliable bus companies operating this trip.

Discover how much the bus trip from Isernia to Rome will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Where are the popular stops in Isernia and Rome?

Stops in Isernia

A - Isernia

Stops in Rome

A - Rome Tiburtina Bus Station

B - Rome Ciampino Airport

C - Rome Fiumicino Airport

D - Castro Pretorio

E - Roma

F - Anagnina

Frequently asked questions on the trip Isernia - Rome

How much does a bus ticket from Isernia to Rome cost?
The bus ticket price from Isernia to Rome starts at US$14. The best way to find cheap bus tickets from Isernia to Rome is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Isernia to Rome?
The average travel time between Isernia and Rome is around 9h 5m, although the fastest bus will take about 2h 10m. This is the time it takes to travel the 150 km that separates the two cities.
How many daily bus connections are there between Isernia and Rome?
The number of buses from Isernia to Rome can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Isernia to Rome by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Isernia to Rome?
When taking the bus from Isernia to Rome, you can travel comfortably and safely with FlixBus, FlixBus.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

30/10

US$26

31/10

US$21

Today

US$25

02/11

US$62

03/11

US$23

04/11

US$24

05/11

US$17

06/11

US$17

The cheapest trip from Isernia to Rome was searched and found on 05 Nov 2025 with a price of US$17

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Isernia to Rome as early as possible.

You can expect to pay from US$17 to US$74 for a bus ticket from Isernia to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at US$17, which is on 2025-11-05.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Isernia and Rome!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Isernia to Rome, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Isernia to Rome will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Isernia to Rome.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Isernia by bus?

Bus from Rome to Isernia

You can also go to Rome by train

Train from Isernia to Rome

Top travelled bus routes

Why choose Busbud?

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Find coaches from Isernia to Rome