Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Isernia | Rome Tiburtina Bus Station | CheapestFastest | ||||
| Bus | Isernia | Rome Fiumicino Airport | No tags | ||||
| Bus | Isernia | Rome Fiumicino Airport | No tags | ||||
| Bus | Isernia | Rome Tiburtina Bus Station | No tags |
Last refresh of the prices: Last Monday at 11:42 PM CET.
Compare 3 ways to go from Isernia to Rome
Among the sustainable travel choices, the carpool stands out as a good way to reach Rome. The journey takes about 2 hours, and with fares starting at just $16, it presents an excellent value for a comfortable ride.
Where are the popular stops in Isernia and Rome?
Stops in Rome
- ALargo Guido Mazzoni, 3, 00162 Roma, Italy
- D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
Compare bus companies
Based on 11400 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. FlixBus ticket prices on this trip start at $20
Frequently asked questions about travelling from Isernia to Rome by bus
What is the travel distance from Isernia to Rome?
The distance between Isernia and Rome is around 150 km (93 miles).
What are the departure and arrival locations for buses traveling from Isernia to Rome?
Buses traveling this route start their trip at Isernia, in Isernia, and end it at Rome Tiburtina Bus Station, in Rome.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Isernia to Rome was searched and found on Nov 24, 2025 with a price of $24To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Isernia to Rome, as early as possible.
You can expect to pay from $24 to $103 for a bus ticket from Isernia to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $24 which is on 2025-11-24.
