Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines Mexico + Greyhound Lines, Inc. | Bus | Houston Uptown/Upper Kirby | Winston Salem Greyhound Bus Station | Cheapest | ||||
 | Bus | Houston Lockwood, (TX - TBC Lockwood) | Winston-salem, (NC - Tienda Mexican El Crystal) | Fastest | ||||
 | Bus | Houston Bus Station | Winston Salem Greyhound Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Houston Bus Station | Winston Salem Greyhound Bus Station | No tags | ||||
FlixBus + Valley Transit + Greyhound Lines, Inc. | Bus | Downtown Gray & Smith | Winston Salem Greyhound Bus Station | No tags |
Last refresh of the prices: Last Thursday at 3:22 PM CST.
Get from Houston to Winston-Salem
The journey takes about 1 day, 7 hours 45 minutes, and with fares starting at just R 2 420, it presents an excellent value for a comfortable ride.
Where are the popular stops in Houston and Winston-Salem?
Stops in Houston
- A
Hillcroft Ave & Southwest Freeway
6590 Southwest Fwy, Houston, TX 77074, USA - B
Downtown Greyhound Station
2121 Main St, Houston, TX 77002 - C
Harrisburg Greyhound Station
7000 Harrisburg Blvd, Houston, TX 77011, USA - D7011 Harrisburg Blvd, Houston, TX 77011, USA
- E
Clay St & Louisiana St
600-698 Clay St, Houston, TX 77002, USA - F
Lockwood Dr & Harvey Wilson Dr
820 Lockwood Dr, Houston, TX 77002, USA
Stops in Winston-Salem
- A
Winston Salem Greyhound Bus Station
100 W 5th St, Winston Salem, NC 27101 - B
E Sprague St
841 E Sprague St, Winston-Salem, NC 27107, USA - C
Winston-Salem Bus Stop
2500 Old Lexington Rd, Winston-Salem, NC 27107, USA - D
1237 Silas Creek Pkwy
1237 Silas Creek Pkwy., Winston-Salem, NC 27127 (Hong Kong King Buffet)
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Frequently asked questions about travelling from Houston, US to Winston-Salem by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Houston to Winston-Salem?
The cheapest bus tickets from Houston to Winston-Salem start at R 2 420. The average price for this route is around R 3 797. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Houston to Winston-Salem?
The average bus journey time from Houston to Winston-Salem is 1d 7h, covering a distance of 1569 km. The fastest bus gets you there in 18h 21m and is operated by Tornado Bus.
Which bus companies service the Houston to Winston-Salem route?
Several major bus companies operate on this route with 17 buses available per day, including services from Greyhound, Tornado Bus, FlixBus, Valley Transit.
What is the earliest and latest departure time for the bus from Houston to Winston-Salem?
The earliest bus departs from Houston to Winston-Salem at 05:00. And the latest bus departs at 23:20.
What are the CO₂ emissions for the bus trip from Houston to Winston-Salem?
A bus trip from Houston to Winston-Salem produces an estimated 39 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Houston to Winston-Salem?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.
Which bus company has the best Wi-Fi from Houston to Winston-Salem?
Based on reviews on Busbud, the bus company Tornado Bus has the best Wi-Fi rating with a score of 4.0.
Which bus company offers the most punctual service from Houston to Winston-Salem?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Houston to Winston-Salem?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tornado Bus, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Houston, US to Winston-Salem was searched and found on 08 Jan 2026 with a price of R 2 468To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to Winston-Salem as early as possible.
You can expect to pay from R 2 468 to R 6 406 for a bus ticket from Houston, US to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 468, which is on 2026-01-08.
Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
