Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Estación Juárez Parada de Autobuses | Santa Ana | Cheapest | ||||
 | Bus | Zapopan Central de Autobuses (Guadalajara) | Santa Ana Col Del Rio | Fastest | ||||
| Bus | Nueva Central | Santa Ana Col Del Rio | No tags | ||||
| Bus | Zapopan Guadalajara | Santa Ana | No tags | ||||
| Bus | Nueva Central | Santa Ana Col Del Rio | No tags |
Last refresh of the prices: Today at 9:18 AM CST.
Get from Guadalajara to Santa Ana
The journey takes about 1 day, 45 minutes, and with fares starting at just R 2 115, it presents an excellent value for a comfortable ride.
Where are the popular stops in Guadalajara and Santa Ana?
Stops in Guadalajara
- ATerminal de Autobuses de Guadalajara, Carretera Libre a Zapotlanejo y entronque carretera a Tonalá Km. 1.5, 44100 Guadalajara
- B
Estación Juárez Parada de Autobuses
Av. Del Federalismo Nte. 800 (esq. Av. Juárez), 44100 Guadalajara, Jalisco, Mexico - C
Terminal de Autobuses de Tlaquepaque
Anillo Periférico Sur #8010, Col. Santa María Tequepexpan, 45601 Tlaquepaque, Jalisco - D
Guadalajara Airport
- E
Terminal de Autobuses Nuevo Milenio de Zapopan
Carretera A Nogales No. 1110, Casi Esq. Av. Aviación (Col. San Juan de Ocotan), 20230 Zapopan, Jal. - F
Forum de Tlaquepaque - Parada de Autobuses
Blvd. Marcelino García Barragán No. 2077 (Col. Lomas del Paradero), 44840, Guadalajara
Stops in Santa Ana
- A
Parada de Autobuses de Santa Ana
Avenida Aldama # 301 entre Cerna y Guerrero - Colonia Centro, 84600 Santa Ana
Compare bus companies
Based on 707 reviews, the company was rated 3.4 stars on Busbud. Travellers were especially satisfied with the seats and the temperature but often complained with the timeliness. Tufesa ticket prices on this trip start at R 2 740
Frequently asked questions about travelling from Guadalajara, MX to Santa Ana, SON, MX by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Guadalajara to Santa Ana?
The cheapest bus tickets from Guadalajara to Santa Ana start at R 2 115. The average price for this route is around R 2 177. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Guadalajara to Santa Ana?
The average bus journey time from Guadalajara to Santa Ana is 1d , covering a distance of 1345 km. The fastest bus gets you there in 21h 50m and is operated by Tufesa.
Which bus companies service the Guadalajara to Santa Ana route?
Several major bus companies operate on this route with 29 buses available per day.
What is the earliest and latest departure time for the bus from Guadalajara to Santa Ana?
The earliest bus departs from Guadalajara to Santa Ana at 00:16. And the latest bus departs at 23:59.
What are the CO₂ emissions for the bus trip from Guadalajara to Santa Ana?
A bus trip from Guadalajara to Santa Ana produces an estimated 34 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Guadalajara, MX to Santa Ana, SON, MX was searched and found on 26 Jan 2026 with a price of R 2 189To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Guadalajara, MX to Santa Ana, SON, MX as early as possible.
You can expect to pay from R 2 189 to R 2 584 for a bus ticket from Guadalajara, MX to Santa Ana, SON, MX based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 189, which is on 2026-01-26.
