Find coaches from Guadalajara, MX to Santa Ana, SON, MX

Previously seen journeys

Next departures from Guadalajara to Santa Ana on 2 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Tufesa
    		Nueva Central
    		Santa Ana Col Del RioNo tags
    Tufesa
      		Nueva Central
      		Santa Ana Col Del RioNo tags
      Tufesa
        		Nueva Central
        		Santa Ana Col Del RioNo tags
        Tufesa
          		Zapopan Central de Autobuses (Guadalajara)
          		Santa Ana Col Del RioNo tags
          Tufesa
            		Zapopan Central de Autobuses (Guadalajara)
            		Santa Ana Col Del RioNo tags

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            Get from Guadalajara to Santa Ana

            This route is served by bus only

            The journey takes about 22 hours 50 minutes, and with fares starting at just US$159, it presents an excellent value for a comfortable ride.

            3bus per day
            22h 50mAverage duration
            1337 kmDistance
            33kgCO₂ emissions

            Bus Guadalajara, MX to Santa Ana, SON, MX: Trip Overview

            Average ticket priceUS$159
            Average bus trip duration22h 50m
            Number of daily buses3
            Earliest bus departure09:00
            Distance1336 km
            Latest bus departure16:30

            Guadalajara to Santa Ana Bus

            Busbud helps you find a bus from Guadalajara to Santa Ana. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

            We make it our job to connect you with the most dependable bus companies that cover bus service from Guadalajara to Santa Ana.

            Discover how much the bus trip from Guadalajara to Santa Ana will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

            Frequently asked questions on the trip Guadalajara, MX - Santa Ana, SON, MX

            1. How much does a bus ticket from Guadalajara to Santa Ana cost?

              The bus ticket price from Guadalajara to Santa Ana starts at US$159. The best way to find cheap bus tickets from Guadalajara to Santa Ana is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

            2. How long is the bus ride from Guadalajara to Santa Ana?

              The average travel time between Guadalajara and Santa Ana is around 22h 50m, although the fastest bus will take about 21h 50m. This is the time it takes to travel the 1345 km that separates the two cities.

            3. How many daily bus connections are there between Guadalajara and Santa Ana?

              The number of buses from Guadalajara to Santa Ana can differ depending on the day of the week. On average, there are 3 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Guadalajara to Santa Ana by comparing and selecting the bus that fits your travel style and budget on Busbud.

            4. Which bus companies travel from Guadalajara to Santa Ana?

              When taking the bus from Guadalajara to Santa Ana, you can travel comfortably and safely with Tufesa.

            5. What are the departure and arrival stations when taking the bus from Guadalajara to Santa Ana?

              Buses travelling between Guadalajara and Santa Ana leave from Nueva Central or Guadalajara Airport and arrive at Parada de Autobuses de Santa Ana.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            30/10
            No data
            31/10
            US$142
            Today
            US$142
            02/11
            US$142
            03/11
            No data
            04/11
            No data
            05/11
            No data
            06/11
            No data
            busbud logoThe cheapest trip from Guadalajara, MX to Santa Ana, SON, MX was searched and found on 31 Oct 2025 with a price of US$142

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Guadalajara, MX to Santa Ana, SON, MX as early as possible.

            You can expect to pay from US$142 to US$142 for a bus ticket from Guadalajara, MX to Santa Ana, SON, MX based on the last 2 days. You can expect to find the cheapest price for the trip at US$142, which is on 2025-11-02.

            About Bus Travel

            Bus Travel Tips

            Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Guadalajara and Santa Ana!

            From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Guadalajara to Santa Ana.

            Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Guadalajara to Santa Ana will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

            Tune out to the fine sounds of your best music playlist on your bus trip from Guadalajara to Santa Ana while indulging in miles on end of beautiful scenic views.

            Did you know?

            It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

            The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

            Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

            Will you be returning to Guadalajara, MX by bus?

            Bus from Santa Ana, SON, MX to Guadalajara, MX

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