Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | 1111 Woodruff Road | BP Gas Station | Cheapest | ||||
 | Bus | Greenville, (SC - Taqueria Guadalajara #3) | Durham | Fastest | ||||
| Bus | 1111 Woodruff Road | BP Gas Station | No tags | ||||
 | Bus | 1116 Woodruff Rd | Durham Greyhound Bus Station | No tags | ||||
 | Bus | 1116 Woodruff Rd | Durham Greyhound Bus Station | No tags |
Last refresh of the prices: Last Sunday at 6:32 PM EST.
Compare 2 ways to travel from Greenville to Durham
Among the sustainable travel choices, the bus stands out as a good way to reach Durham. The journey takes about 4 hours 37 minutes and with fares starting at just R 709, it presents an excellent value for a comfortable ride.
Where are the popular stops in Greenville and Durham?
Stops in Greenville
- A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611 - B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607
Stops in Durham
- A515 W Pettigrew St , Durham, NC 27703
- B
Compare Foods Durham
2000-2004 NC-55, Durham, NC 27704, USA - C
Durham Compare Foods Durham
2000 Avondale Dr, Durham, NC 27704, USA - D
Durham, NC
E Main St at Roxboro St (WB), Durham, NC 27701, USA
Compare bus companies
Frequently asked questions about travelling from Greenville, SC to Durham, NC, US by bus
How much does a bus ticket from Greenville to Durham cost?
The bus ticket price from Greenville to Durham starts at R 709. The best way to find cheap bus tickets from Greenville to Durham is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Greenville to Durham?
The average travel time between Greenville and Durham is around 4h 37m, although the fastest bus will take about 4h 28m. This is the time it takes to travel the 342 km that separates the two cities.
How many daily bus connections are there between Greenville and Durham?
The number of buses from Greenville to Durham can differ depending on the day of the week. On average, there are 9 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Greenville to Durham by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Greenville to Durham?
When taking the bus from Greenville to Durham, you can travel comfortably and safely with Wanda Coach, FlixBus, Tornado Bus.
What are the departure and arrival stations when taking the bus from Greenville to Durham?
Buses travelling between Greenville and Durham leave from Guadalajara Supermarket Bus Stop or Greenville Bus Station and arrive at Durham Greyhound Bus Station, Compare Foods Durham, Durham Compare Foods Durham.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville, SC to Durham, NC, US was searched and found on 28 Nov 2025 with a price of R 847To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Durham, NC, US as early as possible.
You can expect to pay from R 847 to R 2 909 for a bus ticket from Greenville, SC to Durham, NC, US based on the last 2 days. You can expect to find the cheapest price for the trip at R 847, which is on 2025-11-28.
Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Greenville, SC to Durham, NC, US?
The bus is the cheapest travel choice for this destination
