Bus from Greenville, SC to Durham, NC, US: Tickets & Schedules

Next bus departures

Next departures for Greenville to Durham on December 2
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBusBus
1116 Woodruff Rd
Durham Greyhound Bus StationCheapest
Wanda CoachBus
1111 Woodruff Road
BP Gas StationFastest
Wanda CoachBus
1111 Woodruff Road
BP Gas StationNo tags
Greyhound Lines, Inc.Bus
1116 Woodruff Rd
Durham Greyhound Bus StationNo tags
Wanda CoachBus
1111 Woodruff Road
BP Gas StationNo tags

Last refresh of the prices: Yesterday at 9:57 PM EST.

Compare 2 ways to go from Greenville to Durham

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Durham. The journey takes about 4 hours 37 minutes and with fares starting at just $41, it presents an excellent value for a comfortable ride.

9bus per day
4h 37mAverage Duration
217 milesDistance
9kgCO₂ emissions
Average Price$41 - $174Average Duration4h 37m
9kg CO₂e
Average Price$67 - $719Average Duration8h
31kg CO₂e

Frequently asked questions about traveling from Greenville, SC to Durham, NC, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Greenville to Durham?

    The cheapest bus tickets from Greenville to Durham start from $41. The average price for this route is around $56. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Greenville to Durham?

    The average bus trip duration from Greenville to Durham is 4h 37m, covering a distance of 217 miles (349 km). The quickest bus can get you there in 4h 28m and is operated by Tornado Bus.

  3. Which bus companies service the Greenville to Durham route?

    Several major bus companies operate on this route with 9 buses available per day, including services from Wanda Coach, FlixBus, Tornado Bus, Greyhound.

  4. What is the earliest and latest departure time for the bus from Greenville to Durham?

    The earliest bus departs from Greenville to Durham at 7:25am. And the latest bus departs at 10:00pm.

  5. What are the CO₂ emissions for the bus trip from Greenville to Durham?

    A bus trip from Greenville to Durham generates an estimated 9 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Greenville to Durham?

    According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.

  7. Which bus company has the best Wi-Fi from Greenville to Durham?

    Based on reviews on Busbud, the bus company Tornado Bus has the best Wi-Fi rating with a score of 3.6.

  8. Which bus company has the most timely service from Greenville to Durham?

    According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Greenville to Durham?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tornado Bus, with a cleanliness rating of 4.5 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/30
$50
12/01
$50
Today
$48
12/03
$39
12/04
No data
12/05
$36
12/06
No data
12/07
No data
busbud logoThe cheapest trip from Greenville, SC to Durham, NC, US was searched and found on Dec 5, 2025 with a price of $36

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Durham, NC, US, as early as possible.

You can expect to pay from $36 to $165 for a bus ticket from Greenville, SC to Durham, NC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $36 which is on 2025-12-05.

Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Greenville, SC to Durham, NC, US?

busbud logoThe bus is the cheapest travel choice for this destination

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