Find coaches from Gainesville, FL to Panama City, US

Next departures

Next departures from Gainesville to Panama City on 3 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
    		Rosa Parks Station
    		Panama City Beach StationCheapestFastest

    Last refresh of the prices: Yesterday at 5:20 PM EST.

    Accepted payments

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    Get from Gainesville to Panama City

    This route is served by bus only

    The journey takes about 6 hours 40 minutes, and with fares starting at just US$39, it presents an excellent value for a comfortable ride.

    1bus per day
    6h 40mAverage duration
    334 kmDistance
    8kgCO₂ emissions

    Bus Gainesville, FL to Panama City, US: Trip Overview

    Average ticket priceUS$54
    Average bus trip duration6h 40m
    Number of daily buses1
    Earliest bus departure08:20
    Distance333 km
    Latest bus departure16:00

    Gainesville to Panama City Bus

    With Busbud, comparing and booking tickets for a bus from Gainesville to Panama City is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

    We make sure you can find a bus service from Gainesville to Panama City from the most reliable bus companies operating this trip.

    Discover how much the bus trip from Gainesville to Panama City will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

    Frequently asked questions on the trip Gainesville, FL - Panama City, US

    1. How much does a bus ticket from Gainesville to Panama City cost?

      The bus ticket price from Gainesville to Panama City starts at US$39. The best way to find cheap bus tickets from Gainesville to Panama City is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

    2. How long is the bus ride from Gainesville to Panama City?

      The average travel time between Gainesville and Panama City is around 6h 40m, although the fastest bus will take about 6h 5m. This is the time it takes to travel the 328 km that separates the two cities.

    3. How many daily bus connections are there between Gainesville and Panama City?

      The number of buses from Gainesville to Panama City can differ depending on the day of the week. On average, there are 1 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Gainesville to Panama City by comparing and selecting the bus that fits your travel style and budget on Busbud.

    4. Which bus companies travel from Gainesville to Panama City?

      When taking the bus from Gainesville to Panama City, you can travel comfortably and safely with Greyhound.

    5. What are the departure and arrival stations when taking the bus from Gainesville to Panama City?

      Buses travelling between Gainesville and Panama City leave from Rosa Parks Station or Williston Rd & I-75 and arrive at Panama City Greyhound Bus Station.

    Find cheapest prices for buses

    Price is for a one-way ticket for one passenger and based on past searches.

    Best price found
    01/11
    No data
    02/11
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    Today
    US$42
    04/11
    No data
    05/11
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    06/11
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    07/11
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    08/11
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    busbud logoThe cheapest trip from Gainesville, FL to Panama City, US was searched and found on 03 Nov 2025 with a price of US$42

    To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville, FL to Panama City, US as early as possible.

    About Bus Travel

    Bus Travel Tips

    Meet and talk to locals at the bus stations while travelling from Gainesville to Panama City.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

    Start sightseeing the minute your bus leaves the station. If you're on the night bus from Gainesville to Panama City, get comfy and count the stars.

    Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Gainesville to Panama City will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

    Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Gainesville to Panama City.

    Did you know?

    One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

    It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

    Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

    Will you be returning to Gainesville, FL by bus?

    Bus from Panama City, US to Gainesville, FL

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