Find coaches from Gainesville, FL to Charleston, SC, US

Previously seen journeys

Next departures from Gainesville to Charleston on 3 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
    		Gainesville Bus Stop
    		4565 Gaynor Ave, North CharlestonNo tags
    FlixBus + Greyhound
      		Rosa Parks Station
      		4565 Gaynor Ave, North CharlestonNo tags
      FlixBus + Greyhound
        		Gainesville Bus Stop
        		4565 Gaynor Ave, North CharlestonNo tags
        FlixBus + Greyhound
          		Rosa Parks Station
          		4565 Gaynor Ave, North CharlestonNo tags
          Greyhound + FlixBus
            		Rosa Parks Station
            		4565 Gaynor Ave, North CharlestonNo tags

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            Get from Gainesville to Charleston

            This route is served by bus only

            The journey takes about 13 hours 15 minutes, and with fares starting at just US$64, it presents an excellent value for a comfortable ride.

            2bus per day
            13h 15mAverage duration
            422 kmDistance
            11kgCO₂ emissions

            Bus Gainesville, FL to Charleston, SC, US: Trip Overview

            Average ticket priceUS$69
            Average bus trip duration13h 15m
            Number of daily buses2
            Earliest bus departure00:35
            Distance422 km
            Latest bus departure22:40

            Gainesville to Charleston Bus

            With Busbud, comparing and booking tickets for a bus from Gainesville to Charleston is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

            Bus service from Gainesville to Charleston will be provided by the most trusted bus companies.

            Discover how much the bus trip from Gainesville to Charleston will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

            Frequently asked questions on the trip Gainesville, FL - Charleston, SC, US

            1. How much does a bus ticket from Gainesville to Charleston cost?

              The bus ticket price from Gainesville to Charleston starts at US$64. The best way to find cheap bus tickets from Gainesville to Charleston is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

            2. How long is the bus ride from Gainesville to Charleston?

              The average travel time between Gainesville and Charleston is around 13h 15m, although the fastest bus will take about 13h 15m. This is the time it takes to travel the 417 km that separates the two cities.

            3. How many daily bus connections are there between Gainesville and Charleston?

              The number of buses from Gainesville to Charleston can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Gainesville to Charleston by comparing and selecting the bus that fits your travel style and budget on Busbud.

            4. Which bus companies travel from Gainesville to Charleston?

              When taking the bus from Gainesville to Charleston, you can travel comfortably and safely with FlixBus, Greyhound.

            5. What are the departure and arrival stations when taking the bus from Gainesville to Charleston?

              Buses travelling between Gainesville and Charleston leave from Rosa Parks Station or Williston Rd & I-75 and arrive at Charleston Bus Station.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            31/10
            US$63
            01/11
            No data
            Today
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            03/11
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            busbud logoThe cheapest trip from Gainesville, FL to Charleston, SC, US was searched and found on 31 Oct 2025 with a price of US$63

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville, FL to Charleston, SC, US as early as possible.

            About Bus Travel

            Bus Travel Tips

            Meet and talk to locals at the bus stations while travelling from Gainesville to Charleston.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

            Much more than a mere vehicle taking you from Gainesville to Charleston, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

            Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Gainesville to Charleston will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

            Tune out to the fine sounds of your best music playlist on your bus trip from Gainesville to Charleston while indulging in miles on end of beautiful scenic views.

            Did you know?

            The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

            The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

            It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

            Will you be returning to Gainesville, FL by bus?

            Bus from Charleston, SC, US to Gainesville, FL

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